PDZK4 Antibody
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Catalog numberbs-9038R
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PricePlease ask
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Size0.1ml
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Long namePDZK4 Primary Polyclonal Antibody
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Also known asPDZK4 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPDZK4
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SpecificityThis is a highly specific antibody against PDZK4.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PDZK4
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Gene ID number57595
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenPDZK4, also known as PDZRN4L (PDZ domain-containing RING finger protein 4-like protein) or LU1, is a 769 amino acid coiled-coil protein that contains one PDZ (DHR) domain. Encoded by a gene that maps to human chromosome Xq28, PDZK4 is conserved in dog, cow, mouse, rat and zebrafish. PDZK4 localizes to cytoplasm and is expressed specifically in adult and fetal brain. PDZK4 functions as an oncogene and is up-regulated in synovial carcinomas. Treatment of synovial sarcoma cells with small interfering RNA (siRNA) inhibits PDZK4 expression, resulting in tumor-cell growth suppression, suggesting that inappropriate expression of PDZK4 may play a role synovial sarcoma cell proliferation.The exact function of FRMPD2 is unknown. The protein contains a FERM domain: such structures are often involved in signal transduction pathways. Alternatively spliced transcript variants encoding different isoforms have been identified.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesFERM and PDZ domain containing protein 2; PDZ domain containing protein 4; PDZ domain containing protein 5C; PDZ domain containing 4 PDZD5C; PDZK4; PDZK5C;FRPD2_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPDZD4
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Short nameAnti-PDZK4
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePDZK4 Polyclonal Antibody
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Alternative techniqueantibodies
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Gene info
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Identity
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Gene
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Long gene namePDZ domain containing 4
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year2004-04-20
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- PDZ domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data