DC-SIGN (CT) Polyclonal Antibody

#

• Catalog number
  MBS194217
• Price:

  601.81 USD

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• Size
  0.1 mg

# #

• Products_type
  Antibody
• Products_short_name
  [DC-SIGN (CT)]
• Products_name_syn
  [DC-SIGN (CT)]
• Other_names
  [DC-SIGN; CD209 antigen; CD209 antigen; HIV gpl20-binding protein; C-type lectin domain family 4 member L; C-type lectin domain family 4, member L; dendritic cell-specific ICAM-3-grabbing non-integrin 1; dendritic cell-specific intracellular adhesion molecules (ICAM)-3 grabbing non-integrin; CD209 molecule; C-type lectin domain family 4 member L; Dendritic cell-specific ICAM-3-grabbing non-integrin 1]
• Other_gene_names
  [CD209; CD209; CDSIGN; CLEC4L; DC-SIGN; DC-SIGN1; MGC129965; CLEC4L]
• Clonality
  Polyclonal
• Specificity
  DC-SIGN (CT) [This rabbit antibody recognizes aa 384-404 of human DC-SIGN, a dendritic cell receptor.] This antibody recognizes an epitope at the C-terminus of human DC-SIGN, a dendritic cell receptor that can capture and transport HIV from mucosal areas to remote lymph nodes where HIV is then transferred to CD4+ T lymphocytes. Multiple strains of HIV-1, HIV-2, and SIV bind to dendritic cells via DC-SIGN. DC-SIGN is expressed in mucosal tissues, placenta, small intestine, and rectum.
• Form
  100 ug IgG in PBS, pH 7.4, purified by immunoaffinity chromatography.
• Storage_stability
  This antibody is stable for at least one (1) year at -20 degree C. Avoid multiple freeze-thaw cycles.
• Tested_application
  Immunoblot
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Group
  Polyclonals and antibodies
• About
  Polyclonals can be used for Western blot, immunohistochemistry on frozen slices or parrafin fixed tissues. The advantage is that there are more epitopes available in a polyclonal antiserum to detect the proteins than in monoclonal sera.
• French translation
  anticorps

#

• Gene target
  DC-SIGN  
• Gene symbol
  CD209, CLEC4M, UBTD2, WFDC21P, TSPAN14, DCSTAMP, DCX, LAMP3, PDCD1LG2, CCL18
• Short name
  DC-SIGN (CT) Polyclonal Antibody
• Technique
  Polyclonal, Antibody, antibodies against human proteins, antibodies for, Polyclonal antibodies (pAbs) are mostly rabbit or goat antibodies that are secreted by different B cells, whereas monoclonal antibodies come from a single N cell lineage. Pabs are a collection of immunoglobulin molecules that react against a specific antigen, each identifying a different epitope.
• Host
  Rabbit
• Alternative name
  DC-SIGN (CT) polyclonal (antibody to-)
• Alternative technique
  polyclonals, antibodies

Gene info

• Identity
  HGNC:1641
• Gene
  CD209
• Long gene name
  CD209 molecule
• Synonyms gene name
  • CD209 antigen
• Synonyms
  • DC-SIGN
  • hDC-SIGN
  • CDSIGN
  • DC-SIGN1
  • CLEC4L
• GenBank acession
  • M98457
• Locus
  19p13.2
• Discovery year
  2000-07-19
• Entrez gene record
  30835
• Pubmed identfication
  • 1518869
• RefSeq identity
  • NM_021155
• Classification
  • Scavenger receptors
  • C-type lectin domain containing
  • CD molecules
• VEGA ID
  OTTHUMG00000182530

Gene info

• Identity
  HGNC:13523
• Gene
  CLEC4M
• Long gene name
  C-type lectin domain family 4 member M
• Synonyms gene
  • CD209L
  • CD299
• Synonyms gene name
  • CD299 antigen
  • C-type lectin domain family 4, member M
• Synonyms
  • HP10347
  • DC-SIGNR
  • LSIGN
  • DCSIGNR
  • DC-SIGN2
• GenBank acession
  • AB015629
• Locus
  19p13.2
• Discovery year
  2000-09-19
• Entrez gene record
  10332
• Pubmed identfication
  • 10072769
• RefSeq identity
  • NM_014257
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000182432

Gene info

• Identity
  HGNC:24463
• Gene
  UBTD2
• Long gene name
  ubiquitin domain containing 2
• Synonyms
  • DC-UbP
  • MGC30022
• Synonyms name
  • dendritic cell derived ubiquitin like protein
• GenBank acession
  • AF251700
• Locus
  5q35.1
• Discovery year
  2006-11-06
• Entrez gene record
  92181
• Pubmed identfication
  • 12507522
• RefSeq identity
  • NM_152277
• VEGA ID
  OTTHUMG00000130519

Gene info

• Identity
  HGNC:50357
• Gene
  WFDC21P
• Long gene name
  WAP four-disulfide core domain 21, pseudogene
• Synonyms
  • LOC645638
  • lnc-DC
  • LNCDC
• Synonyms name
  • long non-coding RNA, dendritic cell differentiation
  • WDNM1-like, pseudogene
  • lnc-dendritic cell lncRNA
• Locus
  17q23.1
• Discovery year
  2014-06-16
• Entrez gene record
  645638
• Pubmed identfication
  • 24744378
  • 26158411
• RefSeq identity
  • NR_030732
• VEGA ID
  OTTHUMG00000176074

Gene info

• Identity
  HGNC:23303
• Gene
  TSPAN14
• Long gene name
  tetraspanin 14
• Synonyms gene
  • TM4SF14
• Synonyms gene name
  • transmembrane 4 superfamily member 14
• Synonyms
  • DC-TM4F2
  • MGC11352
• GenBank acession
  • AF311903
• Locus
  10q23.1
• Discovery year
  2004-10-19
• Entrez gene record
  81619
• Pubmed identfication
  • 11230166
• RefSeq identity
  • NM_030927
• Classification
  • Tetraspanins
• VEGA ID
  OTTHUMG00000018615

Gene info

• Identity
  HGNC:18549
• Gene
  DCSTAMP
• Long gene name
  dendrocyte expressed seven transmembrane protein
• Synonyms gene
  • TM7SF4
• Synonyms gene name
  • transmembrane 7 superfamily member 4
• Synonyms
  • DC-STAMP
  • FIND
• Synonyms name
  • Dendritic cells (DC)-specific transmembrane protein
  • IL-Four INDuced
• GenBank acession
  • AF305068
• Locus
  8q22.3
• Discovery year
  2004-06-25
• Entrez gene record
  81501
• Pubmed identfication
  • 11169400
  • 11345591
• RefSeq identity
  • NM_030788
• VEGA ID
  OTTHUMG00000164890

Gene info

• Identity
  HGNC:2714
• Gene
  DCX
• Long gene name
  doublecortin
• Synonyms gene name
  • doublecortex; lissencephaly, X-linked (doublecortin)
• Synonyms
  • SCLH
  • DC
  • LISX
  • DBCN
  • XLIS
• Synonyms name
  • doublecortex
• GenBank acession
  • AF040254
• Locus
  Xq23
• Discovery year
  1998-03-24
• Entrez gene record
  1641
• Pubmed identfication
  • 9489699
  • 9489700
• RefSeq identity
  • NM_178153
• Classification
  • Doublecortin superfamily
• VEGA ID
  OTTHUMG00000022204

Gene info

• Identity
  HGNC:14582
• Gene
  LAMP3
• Long gene name
  lysosomal associated membrane protein 3
• Synonyms gene name
  • lysosomal-associated membrane protein 3
• Synonyms
  • LAMP
  • TSC403
  • DC-LAMP
  • DCLAMP
  • CD208
• GenBank acession
  • AB013924
• Locus
  3q27.1
• Discovery year
  2001-06-29
• Entrez gene record
  27074
• Pubmed identfication
  • 9721848
• Classification
  • Lysosome associated membrane proteins
  • CD molecules
• VEGA ID
  OTTHUMG00000158387

Gene info

• Identity
  HGNC:18731
• Gene
  PDCD1LG2
• Long gene name
  programmed cell death 1 ligand 2
• Synonyms
  • PD-L2
  • Btdc
  • PDL2
  • bA574F11.2
  • CD273
  • B7-DC
• Synonyms name
  • B7 dendritic cell molecule
• GenBank acession
  • AF344424
• Locus
  9p24.1
• Discovery year
  2003-11-14
• Entrez gene record
  80380
• Pubmed identfication
  • 11224527
• RefSeq identity
  • NM_025239
• Classification
  • B7 family
  • CD molecules
  • Immunoglobulin like domain containing
  • Receptor ligands
• VEGA ID
  OTTHUMG00000019504

Gene info

• Identity
  HGNC:10616
• Gene
  CCL18
• Long gene name
  C-C motif chemokine ligand 18
• Synonyms gene
  • SCYA18
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 18, pulmonary and activation-regulated
  • chemokine (C-C motif) ligand 18 (pulmonary and activation-regulated)
  • chemokine (C-C motif) ligand 18
• Synonyms
  • DC-CK1
  • PARC
  • AMAC-1
  • DCCK1
  • MIP-4
  • CKb7
• Synonyms name
  • pulmonary and activation-regulated
• GenBank acession
  • Y13710
• Locus
  17q12
• Discovery year
  1997-01-08
• Entrez gene record
  6362
• Pubmed identfication
  • 9233607
  • 10049593
• RefSeq identity
  • NM_002988
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000188410

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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