PBX2 Antibody
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Catalog numberbs-12297R
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PricePlease ask
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Size0.1ml
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Long namePBX2 Primary Polyclonal Antibody
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Also known asPBX2 PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenPBX2
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SpecificityThis is a highly specific antibody against PBX2.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human PBX2
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Gene ID number5089
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Tested ApplicationsWB, IHC-P, IF(IHC-P)
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Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenPbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesG17; Homeobox protein PBX2; HOX12; PBX2MHC; pre-B-cell leukemia homeobox 2; pre-B-cell leukemia transcription factor 2; Protein G17; PBX2_HUMAN.
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolPBX2P1, PBX2
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Short nameAnti-PBX2
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative namePBX2 Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetpre-B-cell leukemia homeobox 2, G17 and HOX12 and PBX2MHC, PBX2 and IDBG-80565 and ENSG00000204304 and 5089, transcription factor binding, nuclei, Pbx2 and IDBG-172072 and ENSMUSG00000034673 and 18515, PBX2 and IDBG-633030 and ENSBTAG00000014421 and 100139739
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Gene info
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Identity
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Gene
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Long gene namePBX homeobox 2 pseudogene 1
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Synonyms gene
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Synonyms gene name
- pre-B-cell leukemia transcription factor pseudogene 1
- pre-B-cell leukemia homeobox 2 pseudogene 1
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Locus
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Discovery year1990-09-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- TALE class homeoboxes and pseudogenes
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namePBX homeobox 2
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Synonyms gene name
- pre-B-cell leukemia transcription factor 2
- pre-B-cell leukemia homeobox 2
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Synonyms
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Locus
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Discovery year1994-12-13
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Entrez gene record
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Pubmed identfication
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Classification
- TALE class homeoboxes and pseudogenes
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data