PBX2 Antibody, Cy7 Conjugated
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Catalog number
bs-12297R-Cy7
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Price
Please ask
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Size
0.1ml
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Long name
PBX2 Polyclonal Antibody, Cy7 Conjugated
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Category
Conjugated Primary Antibodies
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Conjugation
Cy7
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Host Organism
Rabbit (Oryctolagus cuniculus)
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Target Antigen
PBX2
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Specificity
This is a highly specific antibody against PBX2.
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Modification
Unmodified
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Modification site
None
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Clonality
Polyclonal
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Clone
Polyclonal antibody
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Concentration
1ug per 1ul
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Source
KLH conjugated synthetic peptide derived from human PBX2
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Gene ID number
5089
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Tested applications
IF(IHC-P)
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Recommended dilutions
IF(IHC-P)(1:50-200)
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Crossreactivity
Human, Mouse, Rat
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Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Antigen background
Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent at their amino- and carboxy-termini. Two forms of Pbx 1 and Pbx 3 each differ primarily in their carboxy-termini and result from alternative mRNA splicing. Unlike other homeotic selector genes which are expressed transiently during development and differentiation, Pbx gene transcripts are ubiquitously expressed in both fetal and adult tissues and cell lines. Additionally, Pbx 2 and Pbx 3 transcripts are detected in lymphoid cells, which do not express Pbx 1. Pbx 4 expression is confined to the testis, especially to spermatocytes in the pachytene stage of the first meiotic prophase.
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Purification method
This antibody was purified via Protein A.
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Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
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Excitation Emission
743nm/767nm
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Synonyms
G17; Homeobox protein PBX2; HOX12; PBX2MHC; pre-B-cell leukemia homeobox 2; pre-B-cell leukemia transcription factor 2; Protein G17; PBX2_HUMAN.
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Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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Conjugated
These antibodies are excite for emission at 650 nm and detected at a 676 nm wavelengths.
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Additional conjugation
Cy7
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French translation
anticorps
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Gene target
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Gene symbol
PBX2P1, PBX2
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Short name
Anti-PBX2
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Technique
Antibody, antibodies against human proteins, antibodies for, antibody Conjugates
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Isotype
Immunoglobulin G (IgG)
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Label
Cy7
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Alternative name
Anti-PBX2 PAb Cy7
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Alternative technique
antibodies
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Alternative to gene target
pre-B-cell leukemia homeobox 2, G17 and HOX12 and PBX2MHC, PBX2 and IDBG-80565 and ENSG00000204304 and 5089, transcription factor binding, nuclei, Pbx2 and IDBG-172072 and ENSMUSG00000034673 and 18515, PBX2 and IDBG-633030 and ENSBTAG00000014421 and 100139739
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Gene info
Gene info
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Identity
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Gene
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Long gene name
PBX homeobox 2
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Synonyms gene name
- pre-B-cell leukemia transcription factor 2
- pre-B-cell leukemia homeobox 2
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Synonyms
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Locus
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Discovery year
1994-12-13
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Entrez gene record
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Pubmed identfication
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Classification
- TALE class homeoboxes and pseudogenes
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VEGA ID
MeSH Data
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Name
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Concept
Scope note:
Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiers
ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
Product images
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