PAP-AMC, Tyrosinase substrate

• Catalog number
  2858-5
• Price
  Please ask
• Size
  5 mg

• Alternative_name
  1-(4-Methyl-coumarin-7-yl)-3-(4-hydroxyphenyl)urea
• Description
  A useful fluorogenic substrate for tyrosinase. When assaying in phosphate buffer at pH 7.1, the optimal excitation/emission wavelengths are 340/440 nm.
• Structure Available
  yes
• Salt Form
  No
• Molecular Formula
  C₁₇H₁₄N₂O₄
• Molecular Weight
  310.3
• Cell Permeable
  yes
• Purity
  ≥98% by HPLC
• Solubilities
  DMSO (~15 mg/ml)
• Handling
  Protect from air and light
• Tag Line
  A tyrosinase substrate
• Storage Condition
  -20°C
• Shipping Condition
  gel pack
• Shelf Life
  36 months
• SMILES
  O=C(NC1=CC=C(O)C=C1)NC2=CC3=C(C=C2)C(C)=CC(O3)=O
• InChi
  InChI=1S/C17H14N2O4/c1-10-8-16(21)23-15-9-12(4-7-14(10)15)19-17(22)18-11-2-5-13(20)6-3-11/h2-9,20H,1H3,(H2,18,19,22)
• InChi Key
  QALXYEVCEYPEGK-UHFFFAOYSA-N
• Data Sheet Link
• MSDS Available
  Yes

• Gene target
  PAP-AMC   Tyrosinase   substrate  
• Gene symbol
  PAPOLA, RP9, ACP3, MRPS30, PDAP1, TUSC2, PLPP3, PLPP2, PLPP1
• Short name
  PAP-AMC, Tyrosinase substrate
• Alternative name
  PAP-AMC, Tyrosinase substrate

Gene info

• Identity
  HGNC:14981
• Gene
  PAPOLA
• Long gene name
  poly(A) polymerase alpha
• Synonyms
  • PAP
• GenBank acession
  • X76770
• Locus
  14q32.2
• Discovery year
  2001-03-27
• Entrez gene record
  10914
• Pubmed identfication
  • 8302877
  • 10429366
• VEGA ID
  OTTHUMG00000171441

Gene info

• Identity
  HGNC:10288
• Gene
  RP9
• Long gene name
  RP9 pre-mRNA splicing factor
• Synonyms gene name
  • retinitis pigmentosa 9 (autosomal dominant)
• Synonyms
  • PAP-1
• Synonyms name
  • Pim-1 kinase associated protein
• GenBank acession
  • AX016710
• Locus
  7p14.3
• Discovery year
  1994-04-27
• Entrez gene record
  6100
• Pubmed identfication
  • 8513323
  • 15474994
• RefSeq identity
  • NM_203288
• VEGA ID
  OTTHUMG00000152988

Gene info

• Identity
  HGNC:125
• Gene
  ACP3
• Long gene name
  acid phosphatase 3
• Synonyms gene
  • ACPP
• Synonyms gene name
  • acid phosphatase, prostate
• Synonyms
  • ACP-3
  • PAP
  • TM-PAP
• Synonyms name
  • prostatic acid phosphatase
• Locus
  3q22.1
• Discovery year
  1989-05-30
• Entrez gene record
  55
• Pubmed identfication
  • 1375464
  • 2842184
• RefSeq identity
  • NM_001099
• Classification
  • Acid phosphatases
• VEGA ID
  OTTHUMG00000159650

Gene info

• Identity
  HGNC:8769
• Gene
  MRPS30
• Long gene name
  mitochondrial ribosomal protein S30
• Synonyms gene
  • PDCD9
• Synonyms
  • PAP
• GenBank acession
  • AF146192
• Locus
  5p12
• Discovery year
  1999-07-30
• Entrez gene record
  10884
• Pubmed identfication
  • 10640817
  • 11279123
• RefSeq identity
  • NM_016640
• Classification
  • Mitochondrial ribosomal proteins
  • Small subunit mitochondrial ribosomal proteins
• VEGA ID
  OTTHUMG00000096967

Gene info

• Identity
  HGNC:14634
• Gene
  PDAP1
• Long gene name
  PDGFA associated protein 1
• Synonyms
  • PAP1
  • PAP
  • HASPP28
• Synonyms name
  • PDGF associated protein
• GenBank acession
  • U41745
• Locus
  7q22.1
• Discovery year
  2001-02-15
• Entrez gene record
  11333
• Pubmed identfication
  • 8780057
• RefSeq identity
  • NM_014891
• VEGA ID
  OTTHUMG00000154629

Gene info

• Identity
  HGNC:17034
• Gene
  TUSC2
• Long gene name
  tumor suppressor 2, mitochondrial calcium regulator
• Synonyms gene
  • PDAP2
• Synonyms gene name
  • PDGFA associated protein 2
  • tumor suppressor candidate 2
• Synonyms
  • FUS1
  • PAP
  • C3orf11
• GenBank acession
  • AF055479
• Locus
  3p21.31
• Discovery year
  2003-09-25
• Entrez gene record
  11334
• Pubmed identfication
  • 8780057
  • 11593436
• RefSeq identity
  • NM_007275
• VEGA ID
  OTTHUMG00000156877

Gene info

• Identity
  HGNC:9229
• Gene
  PLPP3
• Long gene name
  phospholipid phosphatase 3
• Synonyms gene
  • PPAP2B
• Synonyms gene name
  • phosphatidic acid phosphatase type 2B
• Synonyms
  • PAP-2b
  • LPP3
• GenBank acession
  • AB000889
• Locus
  1p32.2
• Discovery year
  1998-12-02
• Entrez gene record
  8613
• Pubmed identfication
  • 9305923
• RefSeq identity
  • NM_003713
• Classification
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000008160

Gene info

• Identity
  HGNC:9230
• Gene
  PLPP2
• Long gene name
  phospholipid phosphatase 2
• Synonyms gene
  • PPAP2C
• Synonyms gene name
  • phosphatidic acid phosphatase type 2C
• Synonyms
  • PAP-2c
  • LPP2
• GenBank acession
  • AF035959
• Locus
  19p13.3
• Discovery year
  1998-12-02
• Entrez gene record
  8612
• Pubmed identfication
  • 9570154
  • 9607309
• Classification
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000180530

Gene info

• Identity
  HGNC:9228
• Gene
  PLPP1
• Long gene name
  phospholipid phosphatase 1
• Synonyms gene
  • PPAP2A
• Synonyms gene name
  • phosphatidic acid phosphatase type 2A
• Synonyms
  • PAP-2a
  • LPP1
• GenBank acession
  • AB000888
• Locus
  5q11.2
• Discovery year
  1998-12-02
• Entrez gene record
  8611
• Pubmed identfication
  • 9305923
• RefSeq identity
  • NM_176895
• Classification
  • MicroRNA protein coding host genes
  • Phospholipid phosphatases
• VEGA ID
  OTTHUMG00000162240

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