p53, Mutant (Tumor Suppressor Protein 53, Cellular Tumor Antigen p53, Phosphoprotein p53, Antigen NY-CO-13, TP53)

• Catalog number
  GEN609975
• Price
  Please ask
• Size
  200ug

• Also known as
  p53, Mutant
• Other names
  p53; Cellular tumor antigen p53; cellular tumor antigen p53; tumor supressor p53; tumor suppressor p53; p53 cellular tumor antigen; transformation related protein 53; Tumor suppressor p53
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
• Gene name synonims
  Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
• Other gene names
  Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  10F258
• Host organism
  Mouse (Mus musculus)
• Source organism
  Human (Homo sapiens)
• Species reactivity
  Bovine, Chicken, Hamster, Human (Homo sapiens), Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes the 50kD nuclear p53 (mutant forms) as expressed in some carcinomas from sites such as breast (30% of tumours), colon (50% of tumours) and lung (70% of tumours). Species Crossreactivity: mouse, hamster, monkey, rat, bovine, chicken.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Affinity Purified by Protein A affinity chromatography.
• Form Appearance
  Supplied as a liquid in PBS, pH 7.2, 1% BSA, 0.09% sodium azide.
• Concentration
  N/A
• Storage and shipping
  Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
• Tested applications
  Immunohistochemistry (IHC)
• Description
  Antigens are peptides or recombinant or native dependent on the production method. Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.

• Gene target
  p53   Mutant   Tumor   Suppressor   Protein   Cellular   Tumor   p53   Phosphoprotein   p53   NY-CO-13   TP53  
• Gene symbol
  ENTR1, CWC27, UTP14A, NOXA1, NEMF, USH1C, HDAC5, TSHZ1, WNK2, HSPH1
• Short name
  p53, Mutant (Tumor Suppressor Protein 53, Cellular Tumor Antigen p53, Phosphoprotein p53, Antigen NY-CO-13, TP53)
• Technique
  cellular, antigen, antigenes
• Alternative name
  Anti-p53, Mutant (Tumor Suppressor Protein 53, Cellular Tumor Antigen p53, Phosphoprotein p53, Antigen NY-CO-13, TP53)
• Alternative technique
  antigenes
• Alternative to gene target
  tumor protein p53, BCC7 and LFS1 and P53 and TRP53, TP53 and IDBG-26364 and ENSG00000141510 and 7157, MDM2/MDM4 family protein binding, nuclei, Trp53 and IDBG-191036 and ENSMUSG00000059552 and 22059, TP53 and IDBG-635147 and ENSBTAG00000001069 and 281542
• Tissue
  cellular, tumor

Gene info

• Identity
  HGNC:10667
• Gene
  ENTR1
• Long gene name
  endosome associated trafficking regulator 1
• Synonyms gene
  • SDCCAG3
• Synonyms gene name
  • serologically defined colon cancer antigen 3
• Synonyms
  • NY-CO-3
• GenBank acession
  • AF039688
• Locus
  9q34.3
• Discovery year
  1999-08-25
• Entrez gene record
  10807
• Pubmed identfication
  • 9610721
• RefSeq identity
  • NM_006643
• VEGA ID
  OTTHUMG00000020928

Gene info

• Identity
  HGNC:10664
• Gene
  CWC27
• Long gene name
  CWC27 spliceosome associated cyclophilin
• Synonyms gene
  • SDCCAG10
• Synonyms gene name
  • serologically defined colon cancer antigen 10
  • CWC27 spliceosome-associated protein homolog (S. cerevisiae)
  • CWC27 spliceosome-associated protein homolog
  • CWC27 spliceosome associated protein homolog
• Synonyms
  • NY-CO-10
  • SDCCAG-10
• GenBank acession
  • AF039692
• Locus
  5q12.3
• Discovery year
  1999-07-23
• Entrez gene record
  10283
• Pubmed identfication
  • 9610721
  • 19941820
  • 28285769
• RefSeq identity
  • NM_005869
• Classification
  • Cyclophilin peptidylprolyl isomerases
  • Spliceosomal C complex
  • NTC associated proteins
  • Spliceosomal Bact complex
  • Spliceosomal P complex
• VEGA ID
  OTTHUMG00000074069

Gene info

• Identity
  HGNC:10665
• Gene
  UTP14A
• Long gene name
  UTP14A small subunit processome component
• Synonyms gene
  • SDCCAG16
• Synonyms gene name
  • serologically defined colon cancer antigen 16
  • UTP14, U3 small nucleolar ribonucleoprotein, homolog A (yeast)
• Synonyms
  • NY-CO-16
  • Utp14
• GenBank acession
  • AF039694
• Locus
  Xq26.1
• Discovery year
  1999-08-25
• Entrez gene record
  10813
• Pubmed identfication
  • 9610721
  • 16354793
  • 21078665
• RefSeq identity
  • NM_006649
• Classification
  • SSU processome
• VEGA ID
  OTTHUMG00000022378

Gene info

• Identity
  HGNC:10668
• Gene
  NOXA1
• Long gene name
  NADPH oxidase activator 1
• Synonyms gene
  • SDCCAG31
• Synonyms gene name
  • serologically defined colon cancer antigen 31
• Synonyms
  • NY-CO-31
  • FLJ25475
• GenBank acession
  • AF039697
• Locus
  9q34.3
• Discovery year
  1999-08-25
• Entrez gene record
  10811
• Pubmed identfication
  • 9610721
• VEGA ID
  OTTHUMG00000131781

Gene info

• Identity
  HGNC:10663
• Gene
  NEMF
• Long gene name
  nuclear export mediator factor
• Synonyms gene
  • SDCCAG1
• Synonyms gene name
  • serologically defined colon cancer antigen 1
• Synonyms
  • NY-CO-1
  • FLJ10051
• Synonyms name
  • caliban homolog (Drosophila)
• GenBank acession
  • AF039687
• Locus
  14q21.3
• Discovery year
  1999-02-09
• Entrez gene record
  9147
• Pubmed identfication
  • 9610721
  • 10575219
• RefSeq identity
  • NM_004713
• VEGA ID
  OTTHUMG00000170857

Gene info

• Identity
  HGNC:12597
• Gene
  USH1C
• Long gene name
  USH1 protein network component harmonin
• Synonyms gene
  • DFNB18
• Synonyms gene name
  • deafness, autosomal recessive 18
  • Usher syndrome 1C (autosomal recessive, severe)
  • Usher syndrome 1C
• Synonyms
  • PDZ73
  • harmonin
  • NY-CO-37
  • NY-CO-38
  • PDZ-73
  • AIE-75
  • PDZD7C
• Synonyms name
  • harmonin
• GenBank acession
  • AB006955
• Locus
  11p15.1
• Discovery year
  1992-06-08
• Entrez gene record
  10083
• Pubmed identfication
  • 10973247
  • 12107438
• RefSeq identity
  • NM_005709
• Classification
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000166323
• Locus Specific Databases
  • Mutations of the Harmonin Gene
  • CCHMC-BMI & UC Hearing Loss Mutation Database

Gene info

• Identity
  HGNC:14068
• Gene
  HDAC5
• Long gene name
  histone deacetylase 5
• Synonyms
  • KIAA0600
  • NY-CO-9
  • FLJ90614
• GenBank acession
  • AF249731
• Locus
  17q21.31
• Discovery year
  2000-11-28
• Entrez gene record
  10014
• Pubmed identfication
  • 10220385
  • 9610721
• RefSeq identity
  • NM_001015053
• Classification
  • Histone deacetylases, class IIA
• VEGA ID
  OTTHUMG00000181806

Gene info

• Identity
  HGNC:10669
• Gene
  TSHZ1
• Long gene name
  teashirt zinc finger homeobox 1
• Synonyms gene
  • SDCCAG33
• Synonyms gene name
  • serologically defined colon cancer antigen 33
  • teashirt zinc finger 1
  • teashirt family zinc finger 1
• Synonyms
  • NY-CO-33
  • TSH1
• GenBank acession
  • AF039698
• Locus
  18q22.3
• Discovery year
  1999-07-23
• Entrez gene record
  10194
• Pubmed identfication
  • 17586487
• RefSeq identity
  • NM_005786
• Classification
  • ZF class homeoboxes and pseudogenes
  • Zinc fingers C2H2-type
• VEGA ID
  OTTHUMG00000132859

Gene info

• Identity
  HGNC:14542
• Gene
  WNK2
• Long gene name
  WNK lysine deficient protein kinase 2
• Synonyms gene
  • SDCCAG43
  • PRKWNK2
• Synonyms gene name
  • serologically defined colon cancer antigen 43
• Synonyms
  • NY-CO-43
  • KIAA1760
• GenBank acession
  • AJ242724
• Locus
  9q22.31
• Discovery year
  2001-02-07
• Entrez gene record
  65268
• Pubmed identfication
  • 9610721
  • 11571656
• RefSeq identity
  • NM_006648
• Classification
  • WNK lysine deficient protein kinases
• VEGA ID
  OTTHUMG00000020247

Gene info

• Identity
  HGNC:16969
• Gene
  HSPH1
• Long gene name
  heat shock protein family H (Hsp110) member 1
• Synonyms gene name
  • heat shock 105kDa/110kDa protein 1
• Synonyms
  • HSP105B
  • KIAA0201
  • HSP105A
  • NY-CO-25
• GenBank acession
  • AB003333
• Locus
  13q12.3
• Discovery year
  2003-02-19
• Entrez gene record
  10808
• Pubmed identfication
  • 9610721
  • 9931472
• Classification
  • Heat shock 70kDa proteins
• VEGA ID
  OTTHUMG00000016685

MeSH Data

• Name
  Tumor Stem Cell Assay
• Concept
  Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
• Tree numbers
  • E01.370.225.500.383.910
  • E01.370.225.500.388.930
  • E05.200.500.383.910
  • E05.200.500.388.930
  • E05.242.383.910
  • E05.242.417.500
  • E05.337.550.200.800
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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