p53, mutant, aa156-214 (Tumor Suppressor Protein, Oncogene Protein)

  • Catalog number
    GEN633274
  • Price
    Please ask
  • Size
    100ug
  • Also known as
    p53, mutant, aa156-214
  • Other names
    p53; Cellular tumor antigen p53; cellular tumor antigen p53; tumor supressor p53; tumor suppressor p53; p53 cellular tumor antigen; transformation related protein 53; Tumor suppressor p53
  • Category
    Antibodies
  • Subcategory
    Mnoclonal antibodies
  • Gene name
    Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
  • Gene name synonims
    Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
  • Other gene names
    Trp53; Tp53; bbl; bfy; bhy; p44; p53; Tp53; P53; Trp53
  • Clonality
    Monoclonal
  • Immunoglobulin isotype
    IgG1
  • Clone
    3H2805
  • Host organism
    Mouse (Mus musculus)
  • Source organism
    Human (Homo sapiens)
  • Species reactivity
    Bovine, Chicken, Hamster, Monkey, Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
  • Specificity and cross reactivity
    Recognizes an epitope of mutant p53 between amino acids 156-214 which is present in some malignant tissues but which is not present in normal and pre-malignant tissues. Species Crossreactivity: Reactive on all mammals tested (mouse, rat, monkey, cow, hamster and chicken).; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
  • Purification method
    Affinity Purified by Protein A affinity chromatography.
  • Form Appearance
    Supplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
  • Concentration
    N/A
  • Storage and shipping
    Store the antibody at -20 degrees Celsius.
  • Tested applications
    Western Blot (WB), Immunoprecipitation (IP)
  • Description
    Kinase, breast cancer tumor, HRAS like - suppressor protein make genetic suppression restoring the phenotype seen prior to the original background in biological pathways.
MeSH Data
  • Name
  • Concept
    Scope note: A cytologic technique for measuring the functional capacity of tumor stem cells by assaying their activity. It is used primarily for the in vitro testing of antineoplastic agents.
  • Tree numbers
    • E01.370.225.500.383.910
    • E01.370.225.500.388.930
    • E05.200.500.383.910
    • E05.200.500.388.930
    • E05.242.383.910
    • E05.242.417.500
    • E05.337.550.200.800
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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