P505 15 hydrochloride

P505 15 hydrochloride is available 4 times from Biovision labs

  • Description
    P505-15 is a potent, cell-permeable, highly selective, small molecule SYK inhibitor (IC₅₀ = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases.  P505-15 blocks B cell receptor-mediated cell signaling and activation in whole blood (IC₅₀s = 0.27 and 0.28 µM, respectively), as well as Fcɛ receptor 1-mediated basophil degranulation (IC₅₀ = 0.15 µM).
  • Peptide sequence
    N/A
  • CAS number
    1370261-97-4
  • Molecular weight
    429.91
  • Category
    Biochemicals
  • Other name
    2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride; PRT062607; PRT2607; BIIB-057
  • Molecular formula
    C₁₉H₂₃N₉O. HCl
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (>25 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Alternate Name/Synonyms
    2-[[(1R,2S)-2-aminocyclohexyl]amino]-4-[[3-(2H-1,2,3-triazol-2-yl)phenyl]amino]-5-pyrimidinecarboxamide hydrochloride; PRT062607; PRT2607; BIIB-057
  • Appearance
    White solid
  • Formulation
    N/A
  • CAS Number
    1370261-97-4
  • Molecular Formula
    C₁₉H₂₃N₉O. HCl
  • Molecular Weight
    429.91
  • Purity
    ≥98% by HPLC
  • Solubility/Reconstitution Instructions
    DMSO (>25 mg/ml)
  • Handling
    Protect from air and light
  • Tagline
    A potent, cell-permeable, highly selective, small molecule SYK inhibitor
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    N/A
  • PubChem CID
    56948527

9583-25 | P505-15 hydrochloridesize: 25 mg | 869.79 USD

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9583-5 | P505-15 hydrochloridesize: 5 mg | 367.76 USD

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9583-5 | P505-15 hydrochloride for cell activationsize: 5 mg | 267.36 USD

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9583-25 | P505-15 hydrochloride for cell activationsize: 25 mg | 813.75 USD

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