p400 Antibody

• Catalog number
  bs-8279R
• Price
  Please ask
• Size
  0.1ml

• Long name
  p400 Primary Polyclonal Antibody
• Also known as
  p400 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  p400
• Specificity
  This is a highly specific antibody against p400.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human p400
• Gene ID number
  57634
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  NuAR is a multi-protein histone acetyltransferase complex that functions to acetylate the nucleosomal Histones H4 and H2A, thereby activating transcription of select target genes. p400, also known as EP400 (E1A binding protein p400) or mDomino, localizes to the nucleus and is a component of the NuAR complex. Expressed in brain, liver, thymus, lung, spleen, colon and kidney, p400 regulates the transcriptional activity of proteins such as MZF-1 and contributes to the ATPase and helicase activities of NuA4. p400 is a SWI2/ SNF2-related protein that can interact with the adenovirus oncoprotein E1A, thus activating the proapoptotic activity of E1A. The ability of p400 to regulate transcriptional and apoptotic activity suggests that the NuAR complex may be a crucial component of cell proliferation, transformation and, possibly, carcinogenesis. Five isoforms of p400 exist due to alternative splicing events.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  CAG repeat protein 32; CAGH32; DKFZP434I225; Domino homolog; E1A binding protein p400; EP 400; EP400; FLJ42018; FLJ45115; hDomino; KIAA1498; KIAA1818; p400 kDa SWI2/SNF2 related protein; P400 SWI2/SNF2-related protein; TNRC12; Trinucleotide repeat containing 12; Trinucleotide repeat containing gene 12 protein; EP400_HUMAN.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  p400  
• Gene symbol
  EP400
• Short name
  Anti-p400
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  p400 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:11958
• Gene
  EP400
• Long gene name
  E1A binding protein p400
• Synonyms gene
  • TNRC12
• Synonyms gene name
  • trinucleotide repeat containing 12
• Synonyms
  • CAGH32
  • KIAA1498
  • P400
  • KIAA1818
  • DKFZP434I225
• Synonyms name
  • hDomino(p400)
• GenBank acession
  • U80743
• Locus
  12q24.33
• Discovery year
  2000-01-27
• Entrez gene record
  57634
• Pubmed identfication
  • 9225980
  • 11509179
• RefSeq identity
  • NM_015409
• Classification
  • Small nucleolar RNA protein coding host genes
  • Myb/SANT domain containing
• VEGA ID
  OTTHUMG00000187346

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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