NU 7441 for cell activation

NU 7441 for cell activation is available 2 times from Biovision labs

B1117-5 | NU-7441 for cell activationsize: 5 mg | 198.12 USD

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B1117-25 | NU-7441 for cell activationsize: 25 mg | 616.99 USD

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  • Description
    NU-7441 is a potent and selective DNA-PK inhibitor (IC₅₀ = 14 nM). Displays selectivity for DNA-PK over a range of kinases including mTOR, PI 3-K, ATM and ATR. Also enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency, and attenuates nonhomologous end-joining (NHEJ).
  • Peptide sequence
    N/A
  • CAS number
    503468-95-9
  • Molecular weight
    413.49
  • Category
    Biochemicals
  • Other name
    8-(4-Dibenzothienyl)-2-(4-morpholinyl)-4H-1-benzopyran-4-one; KU-57788
  • Molecular formula
    C₂₅H₁₉NO₃S
  • Physical appearance
    Off-white solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98% by HPLC
  • Reconstitute instructions
    DMSO (~ 2 mg/ml with gentle warming)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and light
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    NU-7441 for activation
  • Technique
    activation
  • Alternative name
    NU-7441 to measure cellular activation
  • Tissue
    cell
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