NSC 177223

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  • Catalog number
    N900270
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  • Size
    5 mg
# #
  • Chemical available in other sizes
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  • Cas number
    36707-00-3
  • Chemical s molecular weight
    337.29
  • Chemical s main applications
    NSC 177223 is a Akt/protein kinase B inhibitor. It binds to pleckstrin homologous domain of Akt and blocks Akt membrane translocation. Treatment of cancer cells with NSC 177223 results in inhibition of the kinase activities and induction of cell growth arrest and apoptosis selectively in human cancer cells that harbor constitutively activated Akt.
  • Chemical s category
    Apoptosis, Inhibitors, Pharmaceuticals, Intermediates & Fine Chemicals
  • Other name
    4-Amino-5,8-dihydro-5-oxo-8-β-D-ribofuranosyl-pyrido[2,3-d]pyrimidine-6-carboxamide; API-1
  • Chemical s formula
    C13H15N5O6
  • Physical properties
    No Data Available
  • Melting temperature
    No Data Available
  • Boiling temperature
    No Data Available
  • Chemical s soluble in
    No Data Available
  • Stability conditions
    No Data Available
  • Storage
    No Data Available
#
  • Gene target
    NSC   177223  
  • Short name
    NSC 177223
  • Alternative name
    NSC 177223
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