NQO1 Antibody, FITC Conjugated
NQO1 Antibody, FITC Conjugated is available 1 time from Bioss primary conjugated antibodies labs
- Long nameNQO1 Polyclonal Antibody, FITC Conjugated
- CategoryConjugated Primary Antibodies
- Host OrganismRabbit (Oryctolagus cuniculus)
- Target AntigenNQO1
- SpecificityThis is a highly specific antibody against NQO1.
- Modification siteNone
- ClonePolyclonal antibody
- Concentration1ug per 1ul
- SourceKLH conjugated synthetic peptide derived from human NQO1
- Gene ID number1728
- Swiss ProtP15559
- Tested applicationsIF(IHC-P)
- Recommended dilutionsIF(IHC-P)(1:50-200)
- CrossreactivityHuman, Mouse, Rat
- Crossreactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
- Antigen backgroundThe enzyme apparently serves as a quinone reductase in connection with conjugation reactions of hydroquinons involved in detoxification pathways as well as in biosynthetic processes such as the vitamin K-dependent gamma-carboxylation of glutamate residues in prothrombin synthesis.
- Purification methodThis antibody was purified via Protein A.
- Storage conditionsKeep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
- Excitation Emission494nm/518nm
- SynonymsDTD; QR1; DHQU; DIA4; NMOR1; NMORI; NAD(P)H dehydrogenase [quinone] 1; Azoreductase; DT-diaphorase; Menadione reductase; NAD(P)H:quinone oxidoreductase 1; Phylloquinone reductase; Quinone reductase 1; NQO1
- Gene target
- Short nameNQO1 Antibody, FITC Conjugated
- TechniqueAntibody, antibodies against human proteins, antibodies for, antibody Conjugates, Fluorescein
- Alternative nameNicotinamide adenine dinucleotide(P)H dehydrogenase, quinone 1 (Antibody to), fluorecein coupled
- Alternative techniqueantibodies
- Alternative to gene targetNAD(P)H dehydrogenase, quinone 1, DHQU and DIA4 and DTD and NMOR1 and NMORI and QR1, NQO1 and IDBG-39427 and ENSG00000181019 and 1728, this GO :0003955 and NAD(P)H dehydrogenase (quinone) activity and molecular function this GO :0004128 and cytochrome-b5 reductase activity, acting on NAD(P)H and molecular function this GO :0004784 and superoxide dismutase activity and molecular function this GO :0005515 and protein binding and molecular function this GO :0005737 and cytoplasm and cellular component this GO :0005829 and cytosol and cellular component this GO :0006521 and regulation of cellular amino acid metabolic process and biological process this GO :0006801 and superoxide metabolic process and biological process this GO :0006805 and xenobiotic metabolic process and biological process this GO :0006809 and nitric oxide biosynthetic process and biological process this GO :0006979 and response to oxidative stress and biological process this GO :0007271 and synaptic transmission, cholinergic and biological process this GO :0007568 and aging and biological process this GO :0007584 and response to nutrient and biological process this GO :0009636 and response to toxic substance and biological process this GO :0014070 and response to organic cyclic compound and biological process this GO :0016491 and oxidoreductase activity and molecular function this GO :0019430 and removal of superoxide radicals and biological process this GO :0032355 and response to estradiol and biological process this GO :0034641 and cellular nitrogen compound metabolic process and biological process this GO :0043025 and neuronal cell body and cellular component this GO :0043086 and negative regulation of catalytic activity and biological process this GO :0043525 and positive regulation of neuron apoptotic process and biological process this GO :0044281 and small molecule metabolic process and biological process this GO :0044822 and poly(A) RNA binding and molecular function this GO :0045471 and response to ethanol and biological process this GO :0055114 and oxidation-reduction process and biological process this GO :0070062 and extracellular vesicular exosome and cellular component, cytochrome-b5 reductase activity, this GO :0003955: NAD(P)H dehydrogenase (quinone) activity and also this GO :0004128: cytochrome-b5 reductase activity, acting on NAD(P)H and also this GO :0004784: superoxide dismutase activity and also this GO :0005515: protein binding and also this GO :0016491: oxidoreductase activity and also this GO :0044822: poly(A) RNA binding, this GO :0003955: NAD(P)H dehydrogenase (quinone) activity, this GO :0004128: cytochrome-b5 reductase activity, acting on NAD(P)H, this GO :0004784: superoxide dismutase activity, this GO :0005515: protein binding, this GO :0016491: oxidoreductase activity, this GO :0044822: poly(A) RNA binding, Cytoplasm, Nqo1 and IDBG-190808 and ENSMUSG00000003849 and 18104, NQO1 and IDBG-634590 and ENSBTAG00000020632 and 519632
bs-2184R-FITC | NQO1 Antibody, FITC Conjugatedsize: 0.1ml | 408.79 USD
- Catalog numberbs-2184R-FITC
- Price408.79 USD
- PropertiesIf you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. This Bioss Primary Conjugated Antibodies Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. Bioss Primary Conjugated Antibodies FITC is highly sensitive to pH extremes.
- Additional conjugationAnti-FITC Antibody
- French translationanticorps
1. Gene info
- Long gene nameNAD(P)H quinone dehydrogenase 1
- Synonyms gene
- Synonyms gene name
- diaphorase (NADH/NADPH) (cytochrome b-5 reductase)
- NAD(P)H dehydrogenase, quinone 1
- GenBank acession
- Discovery year2001-06-22
- Entrez gene record
- Pubmed identfication
- Havana BLAST/BLAT
- ConceptScope note:Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy.
- Tree numbers
- Qualifiersclassification, economics, history, instrumentation, methods, standards, trends, utilization, veterinary, statistics & numerical data, ethics
- PubMedfindings assign NQO1 an original role in the regulation of mRNA translation via the control of eukaryotic translation initiation factor 4GI stability by the proteasome.These results indicate that one division of both the accessory and the main olfactory projection maps are composed of sensory neurons that are specialized to reduce environmental and/or endogenously produced quinones via an NQO1-dependent mechanism.These studies also demonstrate that Nqo1 expression and activity in mouse liver are induced via an Nrf2-dependent mechanism.data suggest that NQO1 controls stabilization of p63 and progression towards keratinocyte differentiation leading to normal skin development and presumably skin carcinogenesiscatalase overexpression upregulates BaP-induced NQO1 expression by enhancing the Sp1-AhR-Nrf2 signaling cascade.The p62-Nrf2-Nqo1 cascade functions to assure mammalian longevity by stabilizing mitochondrial integrity.NQO1 does not play a major role in the production of vitamin K hydroquinone and supports the existence of multiple vitamin K reduction pathways.the induction of cellular NAD(+) levels using beta-lapachone (beta-Lap), whose intracellular target is NQO1, prevents the toxic effects of cisplatin through the regulation of PARP-1 and SIRT1 activity.
- Gene ontology - Biological process
- Gene ontology - Cellular component
- Gene ontology - Molecular function
- Entrez Gene
Supplier:Bioss Primary Unconjugated Antibodies