Neuropilin-1 Antibody

• Catalog number
  bs-0693R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Neuropilin-1 Primary Polyclonal Antibody
• Also known as
  Neuropilin-1 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Neuropilin 1
• Specificity
  This is a highly specific antibody against Neuropilin 1.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  880-923/923
• Subcellular location
  Cytoplasm
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human neuropilin-1
• Gene ID number
  8829
• Swiss Prot
  O14786
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  The membrane-bound isoform 1 is a receptor involved in the development of the cardiovascular system, in angiogenesis, in the formation of certain neuronal circuits and in organogenesis outside the nervous system. It mediates the chemorepulsant activity of semaphorins. It binds to semaphorin 3A, The PLGF-2 isoform of PGF, The VEGF-165 isoform of VEGF and VEGF-B. Coexpression with KDR results in increased VEGF-165 binding to KDR as well as increased chemotaxis. It may regulate VEGF-induced angiogenesis. The soluble isoform 2 binds VEGF-165 and appears to inhibit its binding to cells. It may also induce apoptosis by sequestering VEGF-165. May bind as well various members of the semaphorin family. Its expression has an averse effect on blood vessel number and integrity.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NP1; NRP; BDCA4; CD304; VEGF165R; Neuropilin-1; Vascular endothelial cell growth factor 165 receptor; NRP1
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Neuropilin-1  
• Gene symbol
  NETO1, NRP1
• Short name
  Anti-Neuropilin 1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Neuropilin-1 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:13823
• Gene
  NETO1
• Long gene name
  neuropilin and tolloid like 1
• Synonyms gene name
  • neuropilin (NRP) and tolloid (TLL)-like 1
• Synonyms
  • BTCL1
  • BCTL1
• GenBank acession
  • AF448838
• Locus
  18q22.3
• Discovery year
  2001-04-05
• Entrez gene record
  81832
• Pubmed identfication
  • 11943477
  • 12810072
• RefSeq identity
  • NM_138999
• Classification
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000132834

Gene info

• Identity
  HGNC:8004
• Gene
  NRP1
• Long gene name
  neuropilin 1
• Synonyms
  • NRP
  • VEGF165R
  • CD304
• GenBank acession
  • AF016050
• Locus
  10p11.22
• Discovery year
  1998-12-23
• Entrez gene record
  8829
• Pubmed identfication
  • 9529250
  • 9331348
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000019343

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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