NTN3/Netrin-3 Antibody

• Catalog number
  bs-11059R
• Price
  Please ask
• Size
  0.1ml

• Long name
  NTN3/Netrin-3 Primary Polyclonal Antibody
• Also known as
  NTN3/Netrin-3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  NTN3/Netrin-3
• Specificity
  This is a highly specific antibody against NTN3/Netrin-3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human NTN3/Netrin-3
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Netrin proteins are a family of laminin-related secreted proteins that provide guidance signals for axonal growth and cell migration during development. Netrin signaling is dependent on the concentration of calcium outside the cell and the level of PKA activity. In axonal cells, a reduction in PKA activity converts the responsiveness of the axons to the netrin proteins as the cells are repelled, rather than attracted, by the netrin gradient. Neogenin serves as the primary guidance receptor for netrin-3. Netrin-2 and the corresponding mouse homolog netrin-3 are expressed primarily in the lower two-thirds of the spinal cord, and, like netrin-1, they can either attract or repel commissural axons at a distance. Netrin-3 proteins are associated with the axon fibers projecting from motor neurons and from neurons within sympathetic and sensory ganglia, suggesting that netrin-3 may be involved in pathfinding and fasciculation of axon projection. Neogenin serves as the primary guidance receptor for netrin-3. During peripheral nerve development, high netrin-3 expression has been detected in mesenchymal cells, sensory ganglia and muscles. In humans, the gene encoding for the netrin-3 protein is localized to chromosome 16p13.3.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  NET3_HUMAN; Netrin-2-like protein; Netrin-3; NTN2L; NTN3.
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  NTN3/Netrin-3  
• Gene symbol
  NTN3
• Short name
  Anti-NTN3/Netrin-3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  NTN3/Netrin-3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:8030
• Gene
  NTN3
• Long gene name
  netrin 3
• Synonyms gene
  • NTN2L
• Synonyms gene name
  • netrin 2 (chicken)-like
  • netrin 2-like (chicken)
• Synonyms name
  • Netrin-3
• GenBank acession
  • U86759
• Locus
  16p13.3
• Discovery year
  1997-02-05
• Entrez gene record
  4917
• Pubmed identfication
  • 9143507
  • 10366627
• RefSeq identity
  • NM_006181
• Classification
  • Netrins
• VEGA ID
  OTTHUMG00000128867

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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