Nanog Antibody

• Catalog number
  bs-10414R
• Price
  Please ask
• Size
  0.1ml

• Long name
  Nanog Primary Polyclonal Antibody
• Also known as
  Nanog PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  Nanog
• Specificity
  This is a highly specific antibody against Nanog.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  140-175/305
• Subcellular location
  Nucleus
• Source
  KLH conjugated synthetic peptide derived from mouse Nanog
• Gene ID number
  71950
• Swiss Prot
  Q80Z64
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Able to autorepress its expression in differentiating (ES) cells: binds to its own promoter following interaction with ZNF281/ZFP281, leading to recruitment of the NuRD complex and subsequent repression of expression. When overexpressed, promotes cells to enter into S phase and proliferation.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ENK; ecat4; 2410002E02Rik; Homeobox protein NANOG; ES cell-associated protein 4; Early embryo specific expression NK-type homeobox protein; Homeobox transcription factor Nanog; Nanog
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Nanog  
• Gene symbol
  NANOG, NANOGP3, NANOGP8
• Short name
  Anti-Nanog
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  Nanog Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:20857
• Gene
  NANOG
• Long gene name
  Nanog homeobox
• Synonyms
  • FLJ12581
  • FLJ40451
• GenBank acession
  • AB093576
• Locus
  12p13.31
• Discovery year
  2003-09-10
• Entrez gene record
  79923
• Pubmed identfication
  • 12787505
  • 12787504
• RefSeq identity
  • NM_024865
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000166019

Gene info

• Identity
  HGNC:23101
• Gene
  NANOGP3
• Long gene name
  Nanog homeobox pseudogene 3
• Locus
  6p12.1
• Discovery year
  2003-10-07
• Entrez gene record
  340217
• RefSeq identity
  • NG_004095
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000184573

Gene info

• Identity
  HGNC:23106
• Gene
  NANOGP8
• Long gene name
  Nanog homeobox retrogene P8
• Synonyms gene name
  • Nanog homeobox pseudogene 8
• Locus
  15q14
• Discovery year
  2003-10-07
• Entrez gene record
  388112
• Pubmed identfication
  • 23173096
• RefSeq identity
  • NM_001355281
• Classification
  • NKL subclass homeoboxes and pseudogenes
• VEGA ID
  OTTHUMG00000166041

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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