NAME hydrochloride

NAME hydrochloride is available 6 times from Biovision labs

2356-1000 | L-NAME hydrochloridesize: 1 g | 424.54 USD

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2356-500 | L-NAME hydrochloridesize: 500 mg | 390.57 USD

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2356-100 | L-NAME hydrochloridesize: 2X100 mg | 316.99 USD

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2356-100 | L-NAME hydrochloride for cell activationsize: 100 mg | 136.98 USD

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2356-500 | L-NAME hydrochloride for cell activationsize: 500 mg | 296.61 USD

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2356-1000 | L-NAME hydrochloride for cell activationsize: 1 g | 333.97 USD

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  • Description
    A pro-drug of L- NG-Nitro-L-arginine (L-NOARG). Hydrolysis of the methyl ester of L-NAME by cellular esterases converts it into a fully functional L-NOARG that exhibits some selectivity for inhibition of neuronal and endothelial NOS isoforms (Ki values of 15 nM, 39 nM, and 4.4 µM for nNOS (bovine), eNOS (human), and iNOS (mouse), respectively). L-NAME inhibits cGMP formation in endothelial cells with an IC₅₀ of 3.1 µM (in the presence of 30 µM arginine) and reverses the vasodilation effects of acetylcholine in rat aorta rings with an EC₅₀ of 0.54 µM.
  • Peptide sequence
    H-Arg(NO2)-OMeHCl
  • CAS number
    51298-62-5
  • Molecular weight
    269.69
  • Category
    Biochemicals
  • Other name
    NG-Nitro-L-arginine methyl ester hydrochloride
  • Molecular formula
    C₇H₁₅N₅O₄.HCl
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    Yes
  • Is it cell-permeable?
    Yes
  • Purification
    ≥98%
  • Reconstitute instructions
    DMSO (~ 5 mg/ml) or H2O (~50 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and moisture
  • Alternate Name/Synonyms
    NG-Nitro-L-arginine methyl ester hydrochloride
  • Appearance
    White solid
  • Formulation
    N/A
  • CAS Number
    51298-62-5
  • Molecular Formula
    C₇H₁₅N₅O₄.HCl
  • Molecular Weight
    269.69
  • Purity
    ≥98%
  • Solubility/Reconstitution Instructions
    DMSO (~ 5 mg/ml) or H2O (~50 mg/ml)
  • Handling
    Protect from air and moisture
  • Tagline
    A pro-drug of the NOS inhibitor L- NG-Nitro-L-arginine
  • Storage Temp.
    -20°C
  • Shipping Conditions
    gel pack
  • Shelf Life
    36 months
  • MDL Number
    MFCD00039052
  • PubChem CID
    135193
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