Myostatin Antibody (GDF8)

• Catalog number
  F47925-0.08ML
• Price
  Please ask
• Size
  0.08 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Myostatin (GDF8)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IHC, WB, ELISA
• Recommended dilutions
  Western blot: 1:1000,IHC (Paraffin): 1:50
• Notes
  Titration of the Myostatin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Myostatin antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O14793
• Purity
  Purified
• Description
  GDF8 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. This gene is thought to encode a secreted protein which negatively regulates skeletal muscle growth.
• Immunogen
  A portion of amino acids 9-38 from the human protein was used as the immunogen for this Myostatin antibody.
• Storage
  Aliquot the Myostatin antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Myostatin   GDF8  
• Gene symbol
  MSTN
• Short name
  Anti-Myostatin (GDF8)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to Myostatin (GDF8)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:4223
• Gene
  MSTN
• Long gene name
  myostatin
• Synonyms gene
  • GDF8
• Synonyms gene name
  • growth differentiation factor 8
• GenBank acession
  • AF019627
• Locus
  2q32.2
• Discovery year
  1997-09-12
• Entrez gene record
  2660
• Pubmed identfication
  • 9288100
  • 10610713
  • 17003236
• RefSeq identity
  • NM_005259
• Classification
  • Transforming growth factor beta superfamily
• VEGA ID
  OTTHUMG00000132663
• Locus Specific Databases
  • Leiden Muscular Dystrophy pages
  • LRG_200

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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