Munc13 Antibody, ALEXA FLUOR 594

• Catalog number
  bs-11353R-A594
• Price
  Please ask
• Size
  100ul

• Long name
  Munc13 Polyclonal Antibody, ALEXA FLUOR 594 Conjugated
• Also known as
  Anti-Munc13 PAb ALEXA FLUOR 594
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 594
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  Munc13
• Specificity
  This is a highly specific antibody against Munc13.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Munc13
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Munc 13s are homologues of the C. elegans unc-13 gene product. Three brain specific isoforms are expressed in rat: Munc 13-1, -13-2, and -13-3. Munc 13-1 is a peripheral membrane protein that is enriched in synaptosomes and localized to plasma membranes but absent from synaptic vesicles. It has multiple regulatory domains (C1 and C2 domains) that may mediate diacylglycerol, phospholipid, and calcium binding. The C terminus of Munc 13-1 interacts directly with a putative coiled coil domain in the N-terminal part of syntaxin. It has been shown that Munc 13 is involved in priming synaptic vesicles. These activated vesicles can be released immediately on Ca2+ influx.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  590nm/617nm
• Synonyms
  Munc 13; KIAA1032; Munc13-1; Protein unc-13 homolog A; UN13A; Unc 13 homolog A; Unc13a; UNC13A; Unc13h1; UN13A_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR® 594
• Conjugated
  Alexa conjugate 1
• French translation
  anticorps

• Gene target
  Munc13  
• Gene symbol
  UNC13D, UNC13A, UNC13C
• Short name
  Anti-Munc13
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 594
• Alternative name
  Munc13 Polyclonal Antibody, ALEXA FLUOR 594
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:23147
• Gene
  UNC13D
• Long gene name
  unc-13 homolog D
• Synonyms gene name
  • unc-13 homolog D (C. elegans)
• Synonyms
  • Munc13-4
• GenBank acession
  • AK024474
• Locus
  17q25.3
• Discovery year
  2003-10-16
• Entrez gene record
  201294
• RefSeq identity
  • NM_199242
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000179895
• Locus Specific Databases
  • UNC13Dbase: Mutation registry for Familial hemophagocytic lymphohistiocytosis 3
  • CCHMC-BMI & UC Hearing Loss Mutation Database
  • LRG_122

Gene info

• Identity
  HGNC:23150
• Gene
  UNC13A
• Long gene name
  unc-13 homolog A
• Synonyms gene name
  • unc-13 homolog A (C. elegans)
• Synonyms
  • KIAA1032
  • Munc13-1
• GenBank acession
  • AB028955
• Locus
  19p13.11
• Discovery year
  2003-10-16
• Entrez gene record
  23025
• RefSeq identity
  • NM_001080421
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000163877

Gene info

• Identity
  HGNC:23149
• Gene
  UNC13C
• Long gene name
  unc-13 homolog C
• Synonyms gene name
  • unc-13 homolog C (C. elegans)
• Synonyms
  • Munc13-3
  • DKFZp547H074
• GenBank acession
  • AK091491
• Locus
  15q21.3
• Discovery year
  2003-10-16
• Entrez gene record
  440279
• RefSeq identity
  • NM_173166
• Classification
  • UNC13 homologs
• VEGA ID
  OTTHUMG00000172542

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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