MPP5/PALS1 Antibody, ALEXA FLUOR 555

• Catalog number
  bs-11887R-A555
• Price
  Please ask
• Size
  100ul

• Long name
  MPP5/PALS1 Polyclonal Antibody, ALEXA FLUOR 555 Conjugated
• Also known as
  Anti-MPP5/PALS1 PAb ALEXA FLUOR 555
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 555
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  MPP5/PALS1
• Specificity
  This is a highly specific antibody against MPP5/PALS1.
• Modification
  Unmodified
• Modification Site
  None
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human MPP5/PALS1
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  Two highly conserved complexes are responsible for the assembly of tight junctions, the Crumbs-Pals1-Patj complex and the Cdc42-Par6-Par3-aPKC complex. Tight junctions assist in the formation of polarity in the epithelia by establishing a barrier to separate apical and basolateral membranes. Pals1, importantly, mediates interaction between the two complexes via interaction with Par6. Loss of Pals1 function results in delayed polarization, decreased transepithelial electrical resistance and an inability to form lumenal cysts. Because tumors exhibit perturbations in epithelial polarity, Pals1 presents a new potential target in the study of carcinogenesis.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  553nm/568nm
• Synonyms
  FLJ12615; MAGUK p55 subfamily member 5; Membrane protein palmitoylated 5; MPP 5; MPP5; MPP5_HUMAN; PALS 1; PALS1; Protein associated with Lin-7; Stardust Drosophila; Stardust.
• Properties
  For facs or microscopy Alexa 1 conjugate. Very high photo stable ALEXA conjugate. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 555
• French translation
  anticorps

• Gene target
  MPP5/PALS1  
• Gene symbol
  PALS1
• Short name
  Anti-MPP5/PALS1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 555
• Alternative name
  MPP5/PALS1 Polyclonal Antibody, ALEXA FLUOR 555
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:18669
• Gene
  PALS1
• Long gene name
  protein associated with LIN7 1, MAGUK p55 family member
• Synonyms gene
  • MPP5
• Synonyms gene name
  • membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5)
  • membrane palmitoylated protein 5
  • protein associated with LIN7 1, MAGUK family member
• Synonyms
  • FLJ12615
• Synonyms name
  • stardust
  • protein associated with Lin-7 1
• GenBank acession
  • AK022677
• Locus
  14q23.3
• Discovery year
  2002-05-23
• Entrez gene record
  64398
• Pubmed identfication
  • 11927608
• RefSeq identity
  • NM_022474
• Classification
  • Crumbs complex
  • Membrane associated guanylate kinases
  • PDZ domain containing
• VEGA ID
  OTTHUMG00000171243

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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