Mouse Monoclonal [clone ZAP-03] (IgG1) to Human ZAP70 Antibody
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Catalog numberGEN246484
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PricePlease ask
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Size50ug
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Also known asZAP70
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Other namestyrosine-protein kinase ZAP-70 isoform 1; Tyrosine-protein kinase ZAP-70; tyrosine-protein kinase ZAP-70; syk-related tyrosine kinase; 70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; zeta-chain associated protein kinase, 70kD; zeta-chain (TCR) associated protein kinase 70kDa; 70 kDa zeta-chain associated protein; Syk-related tyrosine kinase
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CategoryAntibodies
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SubcategoryMnoclonal antibodies
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Gene nameZAP70
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Gene name synonimsN/A
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Other gene namesZAP70; ZAP70; SRK; STD; TZK; STCD; ZAP-70; SRK
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ClonalityMonoclonal
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Immunoglobulin isotypeIgG1
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CloneZAP-03
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Host organismMouse (Mus musculus)
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Species reactivityHuman (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
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Specificity and cross reactivityRecognizes human ZAP-70, a 70kD tyrosine protein kinase which associates with the T-cell receptor (TCR) zeta chain and undergoes phosphorylation following TCR stimulation. ZAP-70 is primarily expressed in T lymphocytes and natural killer cells, where it plays a key role in T-cell receptor (TCR) signalling. Recent studies suggest that ZAP-70 is also expressed in a population of normal immature B-cells and in B-cells from a sub-set of patients with chronic lymphocytic leukemia; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
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Purification methodProtein A Purified
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Form AppearancePBS, pH 7.4, 0.09% sodium azide.
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Concentration1 miligram per 1 mililiter
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Storage and shippingStore at +4 degrees Celsius for short term storage. For long term storage aliquot and keep the antibody at -20 degrees Celsius. Freeze-thaw cycles should be avoided in order to retain the activity of the antibody.
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Tested applicationsImmunohistochemistry (IHC - Paraffin), Western Blot (WB), Flow Cytometry (FC/FACS)
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PropertiesIf you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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AboutMonoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
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TestMouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
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Latin nameMus musculus
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French translationanticorps
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Gene target
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Gene symbolZAP70, YLPM1, HCG4P3, FAF1, ZC3HAV1
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Short nameMouse Monoclonal [clone ZAP-03] (IgG1) ZAP70 Antibody
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TechniqueMouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
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Hostmouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
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IsotypeIgG1
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SpeciesHuman, Humans, Mouses
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Alternative nameAnti-Mouse Monoclonal [clone ZAP-03] (IgG1) to Human ZAP70
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Alternative techniqueantibodies, murine
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Alternative to gene targetzeta-chain (TCR) associated protein kinase 70kDa, SRK and STCD and STD and TZK and ZAP-70, ZAP70 and IDBG-62509 and ENSG00000115085 and 7535, transferase activity, Cell surfaces, Zap70 and IDBG-145089 and ENSMUSG00000026117 and 22637, ZAP70 and IDBG-629842 and ENSBTAG00000005892 and 504509
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Clone nameZAP-03
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Gene info
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Identity
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Gene
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Long gene namezeta chain of T cell receptor associated protein kinase 70
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Synonyms gene
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Synonyms gene name
- SRK
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1995-05-16
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- SH2 domain containing
- Syk family tyrosine kinases
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameYLP motif containing 1
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Synonyms gene
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Synonyms gene name
- chromosome 14 open reading frame 170
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-11-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Protein phosphatase 1 regulatory subunits
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameHLA complex group 4 pseudogene 3
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Synonyms
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Synonyms name
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Locus
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Discovery year2003-09-01
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameFas associated factor 1
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Synonyms gene name
- Fas (TNFRSF6) associated factor 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1999-12-10
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- UBX domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namezinc finger CCCH-type containing, antiviral 1
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year2003-12-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Poly(ADP-ribose) polymerases
- Zinc fingers CCCH-type
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data