Mouse Monoclonal [clone LT95] (IgG1) to Human CD95 / FAS Antibody

#

• Catalog number
  GEN245324
• Price:

  663.8 USD

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• Size
  50ug

# #

• Also known as
  CD95 / FAS
• Other names
  tumor necrosis factor receptor superfamily member 6 isoform 1; Tumor necrosis factor receptor superfamily member 6; tumor necrosis factor receptor superfamily member 6; Fas AMA; FAS 827dupA; CD95 antigen; FASLG receptor; apoptosis antigen 1; Delta Fas/APO-1/CD95; FAS receptor variant 9; APO-1 cell surface antigen; TNF receptor superfamily member 6; apoptosis-mediating surface antigen FAS; Fas (TNF receptor superfamily, member 6); tumor necrosis factor receptor superfamily, member 6; Fas cell surface death receptor; Apo-1 antigen; Apoptosis-mediating surface antigen FAS; FASLG receptor; CD_antigen: CD95
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  CD95
• Gene name synonims
  FAS
• Other gene names
  FAS; FAS; APT1; CD95; FAS1; APO-1; FASTM; ALPS1A; TNFRSF6; APT1; FAS1; TNFRSF6
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  LT95
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Reacts with CD95 (Fas/APO-1), a 46 kD single chain type I glycoprotein of the tumor necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Ion exchange Chromatography
• Form Appearance
  20 mM Tris/HCl, 15 mM sodium azide, approx., pH 7.4.
• Concentration
  1 miligram per 1 mililiter
• Storage and shipping
  For short term storage keep the antibody at +4 degrees Celsius. For longer storage the antibody should be kept at -20 degrees Celsius. Cycles of freezing and defrosting may denaturate the polypeptide chains of the antibodies and reduce their activity.
• Tested applications
  Immunohistochemistry (IHC - Paraffin), Flow Cytometry (FC/FACS)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

#

• Gene target
  Monoclonal   LT95]   IgG1   CD95   FAS  
• Gene symbol
  FAS, FAS-AS1, FASN
• Short name
  Mouse Monoclonal [clone LT95] (IgG1) CD95 / FAS Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone LT95] (IgG1) to Human CD95 / FAS
• Alternative technique
  antibodies, murine
• Alternative to gene target
  Fas (TNF receptor superfamily, member 6), ALPS1A and APO-1 and APT1 and CD95 and FAS1 and FASTM and TNFRSF6, FAS and IDBG-81669 and ENSG00000026103 and 355, identical protein binding, nuclei, Fas and IDBG-159577 and ENSMUSG00000024778 and 14102, FAS and IDBG-637356 and ENSBTAG00000010785 and 282488
• Clone name
  LT95

Gene info

• Identity
  HGNC:11920
• Gene
  FAS
• Long gene name
  Fas cell surface death receptor
• Synonyms gene
  • FAS1
  • APT1
  • TNFRSF6
• Synonyms gene name
  • tumor necrosis factor receptor superfamily, member 6
  • Fas (TNF receptor superfamily, member 6)
• Synonyms
  • CD95
  • APO-1
• Synonyms name
  • TNF receptor superfamily member 6
• GenBank acession
  • M67454
• Locus
  10q23.31
• Discovery year
  1992-06-25
• Entrez gene record
  355
• Pubmed identfication
  • 1385299
  • 1385309
• Classification
  • Tumor necrosis factor receptor superfamily
  • Death inducing signaling complex
  • CD molecules
• VEGA ID
  OTTHUMG00000018701
• Locus Specific Databases
  • Autoimmune Lymphoproliferative Syndrome Database (ALPSbase): Database of mutations causing human ALPS
  • LOVD at NCBI
  • LRG_134

Gene info

• Identity
  HGNC:37128
• Gene
  FAS-AS1
• Long gene name
  FAS antisense RNA 1
• Synonyms gene
  • FASAS
  • FAS-AS
• Synonyms gene name
  • FAS antisense RNA (non-protein coding)
  • FAS antisense RNA 1 (non-protein coding)
• Synonyms
  • SAF
• Locus
  10q23.31
• Discovery year
  2009-07-16
• Entrez gene record
  100302740
• Pubmed identfication
  • 15829500
  • 24811343
  • 27141526
• RefSeq identity
  • NR_028371
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:3594
• Gene
  FASN
• Long gene name
  fatty acid synthase
• Synonyms
  • FAS
  • SDR27X1
• Synonyms name
  • short chain dehydrogenase/reductase family 27X, member 1
• GenBank acession
  • U26644
• Locus
  17q25.3
• Discovery year
  1994-05-17
• Entrez gene record
  2194
• Pubmed identfication
  • 7835891
  • 7567999
  • 19027726
• RefSeq identity
  • NM_004104
• Classification
  • Short chain dehydrogenase/reductase superfamily
  • 7BS orphan methyltransferases
• VEGA ID
  OTTHUMG00000178527

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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