Mouse Monoclonal [clone A6.4.12] (IgG1) to Human PARP1 / PARP Antibody

• Catalog number
  GEN246444
• Price
  Please ask
• Size
  50ug

• Also known as
  PARP1 / PARP
• Other names
  poly; Poly [ADP-ribose] polymerase 1; poly [ADP-ribose] polymerase 1; poly [ADP-ribose] polymerase 1; poly(ADP-ribose) polymerase; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 1; poly(ADP-ribosyl)transferase; ADP-ribosyltransferase NAD(+); NAD(+) ADP-ribosyltransferase 1; poly (ADP-ribose) polymerase family, member 1; ADP-ribosyltransferase diphtheria toxin-like 1; ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase); poly (ADP-ribose) polymerase 1; ADP-ribosyltransferase diphtheria toxin-like 1; ARTD1; NAD(+) ADP-ribosyltransferase 1; ADPRT 1; Poly[ADP-ribose] synthase 1
• Category
  Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  PARP1
• Gene name synonims
  PARP
• Other gene names
  PARP1; PARP1; PARP; PPOL; ADPRT; ARTD1; ADPRT1; PARP-1; ADPRT 1; pADPRT-1; ADPRT; PPOL; PARP-1; ARTD1; ADPRT 1
• Clonality
  Monoclonal
• Immunoglobulin isotype
  IgG1
• Clone
  A6.4.12
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Drosophila, Xenopus, Hamster, Human (Homo sapiens), Mouse (Mus musculus), Rat (Rattus norvegicus); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Recognizes poly (ADP-ribose) polymerase (PARP), a 116kD nuclear enzyme that has been shown to be cleaved during apoptosis; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  Protein G Purified
• Form Appearance
  PBS, 0.09% sodium azide. Sourced in TCS.
• Concentration
  1 miligram per 1 mililiter
• Storage and shipping
  For long term storage, keep the antibody at -20 degrees Celsius. Short term storage of the antibody can be done at +4 degrees Celsius. Cycles of freezing/defrosting can damage the peptide chains of the antibodies thus reducing the activity.
• Tested applications
  Immunohistochemistry (IHC - Paraffin; IHC - Frozen), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA)
• Properties
  If you buy Antibodies supplied by MBS Monoclonals they should be stored frozen at - 24°C for long term storage and for short term at + 5°C. Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Monoclonal   12]   IgG1   PARP1   PARP  
• Gene symbol
  PARP1, TNKS2, TIPARP, PARP12, TNKS
• Short name
  Mouse Monoclonal [clone A6 4 12] (IgG1) PARP1 / PARP Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  mouse monoclonal, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1
• Species
  Human, Humans, Mouses
• Alternative name
  Anti-Mouse Monoclonal [clone A6.4.12] (IgG1) to Human PARP1 / PARP
• Alternative technique
  antibodies, murine
• Clone name
  A6

Gene info

• Identity
  HGNC:270
• Gene
  PARP1
• Long gene name
  poly(ADP-ribose) polymerase 1
• Synonyms gene
  • PPOL
  • ADPRT
• Synonyms gene name
  • ADP-ribosyltransferase (NAD+; poly (ADP-ribose) polymerase)
  • poly (ADP-ribose) polymerase family, member 1
• Synonyms
  • PARP
  • ARTD1
• GenBank acession
  • BC037545
• Locus
  1q42.12
• Discovery year
  1986-01-01
• Entrez gene record
  142
• Pubmed identfication
  • 10964595
• RefSeq identity
  • NM_001618
• Classification
  • Zinc fingers PARP-type
  • Zinc fingers
  • Poly(ADP-ribose) polymerases
• VEGA ID
  OTTHUMG00000037556

Gene info

• Identity
  HGNC:15677
• Gene
  TNKS2
• Long gene name
  tankyrase 2
• Synonyms gene name
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
• Synonyms
  • TNKL
  • TANK2
  • PARP-5b
  • PARP-5c
  • PARP5B
  • PARP5C
  • pART6
  • ARTD6
• Synonyms name
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 2
• GenBank acession
  • AF342982
• Locus
  10q23.32
• Discovery year
  2001-05-10
• Entrez gene record
  80351
• RefSeq identity
  • NM_025235
• Classification
  • Poly(ADP-ribose) polymerases
  • Sterile alpha motif domain containing
  • Ankyrin repeat domain containing
• VEGA ID
  OTTHUMG00000018747

Gene info

• Identity
  HGNC:23696
• Gene
  TIPARP
• Long gene name
  TCDD inducible poly(ADP-ribose) polymerase
• Synonyms gene name
  • TCDD-inducible poly(ADP-ribose) polymerase
• Synonyms
  • DKFZP434J214
  • DKFZp686N0351
  • DDF1
  • PARP7
  • PARP-7
  • PARP-1
  • pART14
  • RM1
  • ARTD14
• GenBank acession
  • BX537965
• Locus
  3q25.31
• Discovery year
  2003-12-02
• Entrez gene record
  25976
• Pubmed identfication
  • 12851707
• RefSeq identity
  • NM_015508
• Classification
  • Poly(ADP-ribose) polymerases
• VEGA ID
  OTTHUMG00000158646

Gene info

• Identity
  HGNC:21919
• Gene
  PARP12
• Long gene name
  poly(ADP-ribose) polymerase family member 12
• Synonyms gene
  • ZC3HDC1
• Synonyms gene name
  • zinc finger CCCH-type domain containing 1
• Synonyms
  • FLJ22693
  • PARP-12
  • ZC3H1
  • ARTD12
• GenBank acession
  • AL136766
• Locus
  7q34
• Discovery year
  2003-12-10
• Entrez gene record
  64761
• Pubmed identfication
  • 11230166
  • 12851707
• RefSeq identity
  • NM_022750
• Classification
  • Poly(ADP-ribose) polymerases
  • Zinc fingers CCCH-type
• VEGA ID
  OTTHUMG00000157315

Gene info

• Identity
  HGNC:11941
• Gene
  TNKS
• Long gene name
  tankyrase
• Synonyms gene name
  • tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
• Synonyms
  • TIN1
  • TINF1
  • TNKS1
  • PARP-5a
  • PARP5A
  • pART5
  • ARTD5
• Synonyms name
  • TRF1-interacting ankyrin-related ADP-ribose polymerase 1
• GenBank acession
  • AF082556
• Locus
  8p23.1
• Discovery year
  1999-01-08
• Entrez gene record
  8658
• Pubmed identfication
  • 9822378
  • 10198177
• RefSeq identity
  • NM_003747
• Classification
  • Poly(ADP-ribose) polymerases
  • Sterile alpha motif domain containing
  • Ankyrin repeat domain containing
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000090481

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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