Carcinoembryonic Antigen (CEA) /CD66 Mouse Monoclonal Antibody

• Catalog number
  MBS438079
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [Carcinoembryonic Antigen (CEA) /CD66]
• Products_name_syn
  [Carcinoembryonic Antigen-related Cell Adhesion Molecule 5, CEACAM5, CD66, Biliary Glycoprotein (BGP-1)]
• Other_names
  [carcinoembryonic antigen-related cell adhesion molecule 5 isoform 1 preproprotein; Carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen-related cell adhesion molecule 5; carcinoembryonic antigen related cell adhesion molecule 5; Carcinoembryonic antigen; CEA; Meconium antigen 100; CD_antigen: CD66e]
• Products_gene_name
  [CEACAM1]
• Products_gene_name_syn
  [CEACAM5]
• Other_gene_names
  [CEACAM5; CEACAM5; CEA; CD66e; CEA; CEA]
• Clonality
  Monoclonal
• Clone
  [COL-1 + CEA31 + C66/261]
• Reactivity
  Human
• Specificity
  This antibody recognizes proteins of 80-200kDa, identified as different members of CEA family. CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. This MAb does not react with nonspecific cross-reacting antigen (NCA) and with human polymorphonuclear leucocytes. It shows no reaction with a variety of normal tissues and is suitable for staining of formalin/paraffin tissues. CEA is not found in benign glands, stroma, or malignant prostatic cells. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+). Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Description
  Antigens are peptides or recombinant or native dependent on the production method.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  Carcinoembryonic   CEA   CD66   Monoclonal  
• Gene symbol
  CEACAM7, CEACAM5, PSG2
• Short name
  Carcinoembryonic Antigen (CEA) /CD66 Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, antigen, Mouse, antibodies against human proteins, antibodies for, antigenes, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG2a & IgG1, kappa
• Species
  Mouse, Mouses
• Alternative name
  Carcinoembryonic protein (CEA) /CD66 Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, antigenes, murine

Gene info

• Identity
  HGNC:1819
• Gene
  CEACAM7
• Long gene name
  CEA cell adhesion molecule 7
• Synonyms gene
  • CGM2
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 7
  • carcinoembryonic antigen related cell adhesion molecule 7
• Synonyms
  • CEA
• Synonyms name
  • carcinoembryonic antigen gene family member 2
• GenBank acession
  • X98311
• Locus
  19q13.2
• Discovery year
  1991-09-12
• Entrez gene record
  1087
• Pubmed identfication
  • 7806520
  • 9135022
• RefSeq identity
  • NM_006890
• Classification
  • V-set domain containing
  • CEA cell adhesion molecule family
• VEGA ID
  OTTHUMG00000151063

Gene info

• Identity
  HGNC:1817
• Gene
  CEACAM5
• Long gene name
  CEA cell adhesion molecule 5
• Synonyms gene
  • CEA
• Synonyms gene name
  • carcinoembryonic antigen-related cell adhesion molecule 5
  • carcinoembryonic antigen related cell adhesion molecule 5
• Synonyms
  • CD66e
• GenBank acession
  • M17303
• Locus
  19q13.2
• Discovery year
  1986-01-01
• Entrez gene record
  1048
• RefSeq identity
  • NM_004363
• Classification
  • I-set domain containing
  • V-set domain containing
  • CEA cell adhesion molecule family
  • CD molecules
• VEGA ID
  OTTHUMG00000151061

Gene info

• Identity
  HGNC:9519
• Gene
  PSG2
• Long gene name
  pregnancy specific beta-1-glycoprotein 2
• Synonyms gene
  • PSBG2
• Synonyms
  • PSGGB
  • PSG1
  • CEA
• Synonyms name
  • pregnancy-specific beta-1 glycoprotein
  • pregnancy-specific beta-1-glycoprotein 7
  • carcinoembryonic antigen SG8
• Locus
  19q13.31
• Discovery year
  1991-06-06
• Entrez gene record
  5670
• Pubmed identfication
  • 2377620
• RefSeq identity
  • NM_031246
• Classification
  • Pregnancy specific glycoproteins
  • V-set domain containing
• VEGA ID
  OTTHUMG00000151547

MeSH Data

• Name
  Embryo Research
• Concept
  Scope note: Experimentation on, or using the organs or tissues from, a human or other mammalian conceptus during the prenatal stage of development that is characterized by rapid morphological changes and the differentiation of basic structures. In humans, this includes the period from the time of fertilization to the end of the eighth week after fertilization.
• Tree numbers
  • E05.313
• Qualifiers
  economics, ethics, history, legislation & jurisprudence

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