MMP9/ TIMP 1 Complex (Native Protein)
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Catalog number30 100 532
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PricePlease ask
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Size10 µg/ 200µl
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Protein typeNative
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Protein subtypeN/A
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Protein familyMatrix Metalloproteinases, matrixins
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Protein descriptionMMP9 may play an essential role in local proteolysis of the extracellular matrix and in leukocyte migration. Could play a role in bone osteoclastic resorption. Cleaves KiSS1 at a Gly- -Leu bond. Cleaves type IV and type V collagen into large C-terminal three quarter fragments and shorter N-terminal one quarter fragments. Degrades fibronectin but not laminin or Pz-peptide.
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Research area interestsDiseases associated with MMP9 include Metaphyseal Anadysplasia 2 and Metaphyseal Anadysplasia. Among its related pathways are Pathways in cancer and Integrin Pathway.
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Package formliquid
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Tested applicationsDegradation of extracellular Matrix; Screening and evaluation of MMP inhibitors; Antigen standard
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Other namesN/A
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Peptide sequenceN/A
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Available target modificationYes
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Expression systemHuman Blood
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Product Subtypefull length
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Active formYes, after Trypsin activation
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Taguntagged
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Contents50 mM Tris-HCl, pH 7.0, 200 mM NaCl, 5 mM CaCl2, 1 μM ZnCl2, 0.05 % Brij-35, 0.05 % NaN3
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Protein purity>95%
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Molecular weightThe 92 kDa form represents the monomer, the 29 kDa protein band represents TIMP 1
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UniProt numberN/A
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Gene numberN/A
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AbbreviationN/A
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Full nameN/A
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Other desciptionProgelatinase B complex is isolated from human blood.
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PurificationMentioned in the data sheet
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PubMed citationsSee the data sheet
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WarningsFor Research Use only.
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Shipping conditionsdry ice
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Storage conditionStore at -70°C
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Technical datasheetContact us to receive the datasheet
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Gene target
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Gene symbolMMP9, TIMP1
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Short nameMMP9/ TIMP 1 Complex (Native Protein)
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SpeciesHomo sapiens
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Alternative namematrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)/ TIMP 1 aggregate (Native Protein)
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Alternative to gene targetmatrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase), CLG4B and GELB and MANDP2 and MMP-9, MMP9 and IDBG-78722 and ENSG00000100985 and 4318, identical protein binding, Extracellular, Mmp9 and IDBG-212451 and ENSMUSG00000017737 and 17395, MMP9 and IDBG-642990 and ENSBTAG00000020676 and 282871
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Gene info
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Identity
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Gene
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Long gene namematrix metallopeptidase 9
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Synonyms gene
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Synonyms gene name
- matrix metalloproteinase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
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Locus
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Discovery year1990-03-14
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Entrez gene record
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Pubmed identfication
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Classification
- M10 matrix metallopeptidases
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameTIMP metallopeptidase inhibitor 1
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Synonyms gene
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Synonyms gene name
- tissue inhibitor of metalloproteinase 1 (erythroid potentiating activity, collagenase inhibitor)
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Synonyms
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Locus
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Discovery year1986-01-01
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Entrez gene record
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RefSeq identity
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Classification
- Tissue inhibitor of metallopeptidases
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VEGA ID
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Locus Specific Databases