MM Panel FISH Probe (P53/D13S319; RB1/1q21; IGH)

Description

any of various testing devices or substances as (1) a pointed metal tip for making electrical contact with a circuit element being checked (2) a usually small object that is inserted into something so as to test conditions at a given point (3) a device used to penetrate or send back information especially from outer space or a celestial body (4) a device (as an ultrasound generator) or a substance (as radioactively labeled DNA) used to obtain specific information for diagnostic or experimental purposes

Gene target

Panel FISH P53/D13S319 RB1/1q21 IGH
Gene symbol

IGH, RB1-DT, TP53, SH3PXD2A, RB1
Short name

MM Panel FISH Probe (P53/D13S319; RB1/1q21; IGH)
Technique

probe, probes
Species

Fish, Fishes
Alternative name

millimeter Panel fluorescence-emitting hybridization Probe (P53/D13S319; retinoblastoma 1/1q21; IGH)
Alternative technique

probes
Alternative to gene target

retinoblastoma 1, OSRC and p105-Rb and pp110 and PPP1R130 and pRb and RB, RB1 and IDBG-32092 and ENSG00000139687 and 5925, phosphoprotein binding, nuclei, Rb1 and IDBG-179829 and ENSMUSG00000022105 and 19645, BT.68871 and IDBG-629082 and ENSBTAG00000006640 and 534712
Tissue

panel

Identity

HGNC:9884
Gene

RB1
Long gene name

RB transcriptional corepressor 1
Synonyms gene
- OSRC
Synonyms gene name
- osteosarcoma
- retinoblastoma 1
Synonyms
- RB
- PPP1R130
Synonyms name
- prepro-retinoblastoma-associated protein
- protein phosphatase 1, regulatory subunit 130
GenBank acession
- M15400
Locus

13q14.2
Discovery year

1986-01-01
Entrez gene record

5925
Pubmed identfication
- 1857421
- 15057823
RefSeq identity
- NM_000321
Classification
- Receptor ligands
VEGA ID

OTTHUMG00000016900
Locus Specific Databases
- RB1-LSDB
- LRG_517

Name

In Situ Hybridization, Fluorescence
Concept

Scope note: A type of IN SITU HYBRIDIZATION in which target sequences are stained with fluorescent dye so their location and size can be determined using fluorescence microscopy. This staining is sufficiently distinct that the hybridization signal can be seen both in metaphase spreads and in interphase nuclei.
Tree numbers
- E01.370.225.500.620.670.325.350
- E01.370.225.750.600.670.325.350
- E05.200.500.620.670.325.350
- E05.200.750.600.670.325.350
- E05.393.285.350
- E05.393.661.475.350
Qualifiers

ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data