MEF2A Antibody / Myocyte-specific enhancer factor 2A

• Catalog number
  R32383
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  MEF2A / Myocyte-specific enhancer factor 2A
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P
• Recommended dilutions
  Western blot: 0.1-0.5ug/ml,IHC (FFPE): 0.5-1ug/ml
• Notes
  Optimal dilution of the MEF2A antibody should be determined by the researcher.
• Intented use
  This MEF2A antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q02078
• Purity
  Antigen affinity
• Description
  Myocyte-specific enhancer factor 2A is a transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor- and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter. [UniProt]
• Immunogen
  Amino acids DGSDREDPRGDFHSPIVLGRPPNTEDRESPSVKRMRMDAWVT from the human protein were used as the immunogen for the MEF2A antibody.
• Storage
  After reconstitution, the MEF2A antibody may be kept for up to one month refrigerated at +4 degrees C.For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Localization
  Nuclear
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Additional description
  Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.
• French translation
  anticorps

• Gene target
  MEF2A   Myocyte-specific   enhancer   factor  
• Gene symbol
  MEF2A
• Short name
  Anti-MEF2A / Myocyte-specific enhancer factor 2A
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to MEF2A / Myocyte-specific enhancer factor 2A
• Alternative technique
  antibodies
• Alternative to gene target
  myocyte enhancer factor 2A, ADCAD1 and mef2 and RSRFC4 and RSRFC9, MEF2A and IDBG-31725 and ENSG00000068305 and 4205, protein dimerization activity, nuclei, Mef2a and IDBG-192076 and ENSMUSG00000030557 and 17258, MEF2A and IDBG-628642 and ENSBTAG00000010649 and 407231

Gene info

• Identity
  HGNC:6993
• Gene
  MEF2A
• Long gene name
  myocyte enhancer factor 2A
• Synonyms
  • RSRFC4
  • RSRFC9
• Locus
  15q26.3
• Discovery year
  1995-02-08
• Entrez gene record
  4205
• Pubmed identfication
  • 1516833
• Classification
  • Myocyte enhancer factor 2 proteins
  • MADS box family
• VEGA ID
  OTTHUMG00000171937

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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