MDC Recombinant Protein

• Catalog number
  40-387
• Price
  Please ask
• Size
  0.005 mg, 0.02 mg

• About recombinant protein
  MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells and exerts HIV suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity but retains HIV suppressive activity. Recombinant human MDC is an 8.0 kDa protein containing 67 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
• Other name of the recombinant
  MDC, ABCD-1, SCYA22, STCP-1, DC/B-CK, A-152E5.1, MDC, C-C motif chemokine 22, CC chemokine STCP-1
• Recombinant in
  E. coli
• SEQUENCE
  YGANMEDSVC CRDYVRYRLP LRVVKHFYWT SDSCPRPGVV LLTFRDKEIC ADPRVPWVKM ILNKLSQ
• Activity
  Biological activity was determined by its ability to chemoattract human T cells using a concentration range of 10.0 - 100.0 ng/mL.
• Keep at
  The lyophilized MDC recombinant protein is stable for at least 2 years from date of receipt at -20˚C. Reconstituted MDC is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚C. As with any protein, exposing MDC recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
• Rec PROTEIN GI
  22538804
• Accession nr
  NP_002981.2
• Pureity
  Greater than 98% by SDS-PAGE gel and HPLC analyses.Endotoxin level is less than 0.1 ng per μg (1EU/μg).
• About
  This product is for research use only.
• Protein s origin
  Human
• Vial
  Lyophilized
• NCBI ID
  6367
• Gene name
  chemokine (C-C motif) ligand 22
• Source
  Homo sapiens
• Uniprot
  O00626
• Pictures of recombinant
• Rec pdf
• Additional source
  Recombinants or rec. proteins
• Group
  recombinants

• Gene target
  MDC   Protein  
• Gene symbol
  CCL22
• Short name
  MDC Recombinant Protein
• Technique
  Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. proscience advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
• Alternative name
  MDC Rec. Protein
• Alternative technique
  rec

Gene info

• Identity
  HGNC:10621
• Gene
  CCL22
• Long gene name
  C-C motif chemokine ligand 22
• Synonyms gene
  • SCYA22
• Synonyms gene name
  • small inducible cytokine subfamily A (Cys-Cys), member 22
  • chemokine (C-C motif) ligand 22
• Synonyms
  • MDC
  • STCP-1
  • ABCD-1
  • DC/B-CK
  • A-152E5.1
  • MGC34554
• GenBank acession
  • U83171
• Locus
  16q21
• Discovery year
  1997-08-22
• Entrez gene record
  6367
• Pubmed identfication
  • 9151897
  • 9691168
• RefSeq identity
  • NM_002990
• Classification
  • Chemokine ligands
• VEGA ID
  OTTHUMG00000133454

MeSH Data

• Name
  Primary Cell Culture
• Concept
  Scope note: The initial culturing of cells derived directly from fresh TISSUES.
• Tree numbers
  • E01.370.225.500.223.500
  • E05.200.500.265.500
  • E05.242.223.500
  • E05.481.500.249.500
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Similar products