FIG4/SAC3 Antibody
-
Catalog numberbs-11690R
-
PricePlease ask
-
Size0.1ml
-
-
Long nameFIG4/SAC3 Primary Polyclonal Antibody
-
Also known asFIG4/SAC3 PAb
-
CategoryPrimary Antibodies
-
ConjugationUnconjugated
-
Target AntigenFIG4/SAC3
-
SpecificityThis is a highly specific antibody against FIG4/SAC3.
-
Modification sNone
-
Modification site sUnmodified antibody
-
ClonalityPolyclonal antibody
-
Clone numberPolyclonal antibody
-
Concentration1ug per 1ul
-
SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human FIG4
-
Tested ApplicationsWB, IHC-P, IF(IHC-P)
-
Recommended dilutionsWB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
-
Cross reactivityHuman, Mouse, Rat
-
Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
-
Background of the target antigenFIG4 is a 907 amino acid protein that contains one SAC domain through which it is thought to function as a phosphoinositide phosphatase that may play an important role in signal transduction and vesicle trafficking. Defects in the gene encoding FIG4 are the cause of Charcot-Marie-Tooth disease type 4J (CMT4J) and amyotrophic lateral sclerosis type 11 (ALS11), both of which negatively affect the nervous system. CMT4J is a recessive demyelinating disorder of the peripheral nervous system and is characterized by reduced motor nerve conduction velocities and axonal degeneration. Unlike CMT4J, ALS11 is characterized by the degeneration of upper motor neurons in the brain and lower neurons in the spinal cord, causing paralysis and, ultimately, death.
-
Purification methodThis antibody was purified via Protein A.
-
Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
-
Synonym names5-bisphosphate 5-phosphatase; Fig4; FIG4_HUMAN; KIAA0274; ALS11; Phosphatidylinositol 3; hSac3; Phosphatidylinositol 3,5 bisphosphate 5 phosphatase; Polyphosphoinositide phosphatase; SAC domain containing protein 3; SAC domain-containing protein 3; SAC3.
-
PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
-
French translationanticorps
-
Gene target
-
Gene symbolFIG4, MCM3AP
-
Short nameAnti-FIG4/SAC3
-
TechniqueAntibody, antibodies against human proteins, antibodies for
-
HostRabbit (Oryctolagus cuniculus)
-
IsotypeImmunoglobulin G (IgG)
-
Alternative nameFIG4/SAC3 Polyclonal Antibody
-
Alternative techniqueantibodies
-
Gene info
-
Identity
-
Gene
-
Long gene nameFIG4 phosphoinositide 5-phosphatase
-
Synonyms gene
-
Synonyms gene name
- KIAA0274
- FIG4 homolog (S. cerevisiae)
- FIG4 homolog, SAC1 lipid phosphatase domain containing (S. cerevisiae)
-
Synonyms
-
GenBank acession
-
Locus
-
Discovery year2003-11-26
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Phosphoinositide phosphatases
-
VEGA ID
-
Locus Specific Databases
Gene info
-
Identity
-
Gene
-
Long gene nameminichromosome maintenance complex component 3 associated protein
-
Synonyms gene name
- minichromosome maintenance deficient (S. cerevisiae) 3-associated protein
- MCM3 minichromosome maintenance deficient 3 (S. cerevisiae) associated protein
-
Synonyms
-
Synonyms name
-
GenBank acession
-
Locus
-
Discovery year1999-03-04
-
Entrez gene record
-
Pubmed identfication
-
RefSeq identity
-
Classification
- Lysine acetyltransferases
- Transcription and export complex 2
-
VEGA ID
MeSH Data
-
Name
-
ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
-
Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
-
Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data