MCP-1 (MCAF), rat recombinant
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Catalog number4224-10
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Price:
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Size10 ug
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SynonymsMonocyte Chemotactic Protein-1, CCL2, MCAF
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Alternative_namesMonocyte Chemotactic Protein-1, CCL2, MCAF, Monocyte chemoattractant protein 1, Monocyte secretory protein JE, Small-inducible cytokine A2
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DescriptionChemoattractant for monocytes and basophils
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RecombinantYes
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SourceE. coli
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Purity by SDS PAGE≥98%
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AssaySDS-PAGE
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Purity≥98%
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Biological activityDetermined by its ability to chemoattract human monocytes using a concentration range of 10-100 ng/ml.
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Results10-100 ng/ml.
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Molecular Weight14.0 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized protein
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Physical form descriptionSterile filtered and then lyophilized with no additives. The protein may appear as a haze or film which is difficult to see at the bottom of the vial.
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Reconstitution InstructionsReconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. This solution can then be diluted into other buffered solutions and stored at 4°C for 1 week or –20°C for future use.
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Background InformationMacrophage/monocyte chemoattractant protein-1 (MCP-1) plays an important role in the inflammatory response of blood monocytes and tissue microphages. Recombinant rat MCP-1 is a 14.0 kDa protein containing 125 amino acid residues.
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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AboutRats are used to make rat monoclonal anti mouse antibodies. There are less rat- than mouse clones however. Rats genes from rodents of the genus Rattus norvegicus are often studied in vivo as a model of human genes in Sprague-Dawley or Wistar rats.
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Latin nameRattus norvegicus
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCCL2, CAPG, CCL13, CCL8, SLC25A33, CCR2, CD46, CCL7, IGHVII-1-1, MIR1-1
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Short nameMCP-1 (MCAF), recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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HostRat
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SpeciesRat, Rats
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Alternative nameMCP-1 (MCAF), rat Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 2
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Synonyms gene
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Synonyms gene name
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
- chemokine (C-C motif) ligand 2
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1990-07-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namecapping actin protein, gelsolin like
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Synonyms gene
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Synonyms gene name
- capping protein (actin filament), gelsolin-like
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-12-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Gelsolin/villins
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 13
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 13
- chemokine (C-C motif) ligand 13
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-02-11
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 8
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Synonyms gene
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Synonyms gene name
- small inducible cytokine subfamily A (Cys-Cys), member 8 (monocyte chemotactic protein 2)
- chemokine (C-C motif) ligand 8
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Synonyms
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GenBank acession
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Locus
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Discovery year1996-11-14
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namesolute carrier family 25 member 33
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Synonyms gene name
- solute carrier family 25, member 33
- solute carrier family 25 (pyrimidine nucleotide carrier), member 33
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Synonyms
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GenBank acession
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Locus
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Discovery year2006-09-21
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Solute carriers
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine receptor 2
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Synonyms gene
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Synonyms gene name
- chemokine (C-C motif) receptor 2
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Synonyms
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Locus
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Discovery year1995-05-30
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- C-C motif chemokine receptors
- CD molecules
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameCD46 molecule
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Synonyms gene
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Synonyms gene name
- antigen identified by monoclonal antibody TRA-2-10
- membrane cofactor protein (CD46, trophoblast-lymphocyte cross-reactive antigen)
- CD46 antigen, complement regulatory protein
- CD46 molecule, complement regulatory protein
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Synonyms
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GenBank acession
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Locus
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Discovery year1988-08-31
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Sushi domain containing
- Complement system regulators and receptors
- CD molecules
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VEGA ID
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Locus Specific Databases
Gene info
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Identity
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Gene
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Long gene nameC-C motif chemokine ligand 7
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Synonyms gene
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Synonyms gene name
- small inducible cytokine A7 (monocyte chemotactic protein 3)
- chemokine (C-C motif) ligand 7
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Synonyms
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Synonyms name
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GenBank acession
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Locus
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Discovery year1993-11-04
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Chemokine ligands
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameimmunoglobulin heavy variable (II)-1-1 (pseudogene)
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Synonyms gene name
- immunoglobulin heavy variable (II)-1-1
- immunoglobulin heavy variable (II)-1-1 pseudogene
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Synonyms
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GenBank acession
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Locus
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Discovery year2000-04-17
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Entrez gene record
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RefSeq identity
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Classification
- Immunoglobulin heavy locus at 14q32.33
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VEGA ID
Gene info
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Identity
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Gene
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Long gene namemicroRNA 1-1
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Synonyms gene
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Synonyms
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Locus
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Discovery year2004-04-23
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Entrez gene record
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RefSeq identity
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Classification
- MicroRNA MIR1/206 family
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data