MAGE-1 (Target for Cancer Immunotherapy) Mouse Monoclonal Antibody

• Catalog number
  MBS438129
• Price
  Please ask
• Size
  0.02 mg (With BSA & Azide at 0.2mg/mL)

• Products_type
  Antibody
• Products_short_name
  [MAGE-1]
• Products_name_syn
  [MZ2 E, cancer/testis antigen 1.1, CT1.1, MAGE1A, MAGEA1, Melanoma antigen family A 1, Melanoma associated antigen 1, Melanoma associated antigen MZ2 E]
• Other_names
  [melanoma-associated antigen 1; Melanoma-associated antigen 1; melanoma-associated antigen 1; MAGE family member A1; Antigen MZ2-E; Cancer/testis antigen 1.1; CT1.1; MAGE-1 antigen]
• Products_gene_name
  [MAGEA1]
• Other_gene_names
  [MAGEA1; MAGEA1; CT1.1; MAGE1; MAGE1; MAGE1A; CT1.1]
• Clonality
  Monoclonal
• Clone
  [MA454]
• Reactivity
  Human, Rat, Dog
• Specificity
  Recognizes a protein of 42-46kDa, identified as MAGE-1. This MAb does not cross-react with MAGE-2, -3, -4, -6 -9, -10, -or -12 protein. Human malignant neoplasms carry rejection antigens that are recognized by the patients' autologous, tumor directed and specific, cytolytic, CD8+ T lymphocyte clones (CTL). The MAGE family of genes codes an important group of antigens. It was identified that melanomas and primary glial brain tumors express common melanoma associated antigens (MAAs). Because MAGE-1 is expressed on a significant proportion of human neoplasms of various histological types (melanoma, brain tumors of glial origin, neuroblastoma, non-small cell lung cancer, breast, gastric, colorectal, ovarian, renal cell carcinomas) and not on normal tissues, the encoded antigen may serve as a marker of early detection and target for cancer immunotherapy.
• Form
  200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Storage_stability
  Antibody with azide - store at 2 to 8 degree C. Antibody without azide - store at -20 to -80 degree C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
• Tested_application
  Flow Cytometry (FC/FACS), Immunofluorescence (IF), Immunohistochemistry (IHC) Formalin
• Properties
  If you buy Antibodies supplied by MyBioSource they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• About
  Monoclonals of this antigen are available in different clones. Each murine monoclonal anibody has his own affinity specific for the clone. Mouse monoclonal antibodies are purified protein A or G and can be conjugated to FITC for flow cytometry or FACS and can be of different isotypes.
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus
• French translation
  anticorps

• Gene target
  MAGE-1   for   Cancer   Immunotherapy   Monoclonal  
• Gene symbol
  MAGED4, MAGED2, MAGEA1, MAGEA4, TRO, MAGEB5, MAGEC2, MAGEB6, MAGEC3, MAGEB2
• Short name
  MAGE-1 ( for Cancer Immunotherapy) Mouse Monoclonal Antibody
• Technique
  Mouse monoclonal, Antibody, Mouse, antibodies against human proteins, antibodies for, Monoclonals or monoclonal antibodies, mouses, mouse monoclonals
• Host
  Mouse, Murine monoclonal antibodies or Mabs are often conjugated and the isotype is IgG.
• Isotype
  IgG1, kappa
• Species
  Mouse, Mouses
• Alternative name
  MAGE-1 (Target to measure Cancer Immunotherapy) Mouse monoclonal (antibody to-)
• Alternative technique
  antibodies, murine
• Disease
  cancer

Gene info

• Identity
  HGNC:23793
• Gene
  MAGED4
• Long gene name
  MAGE family member D4
• Synonyms gene name
  • melanoma antigen family D4
• Synonyms
  • MAGE1
  • MGC3210
  • KIAA1859
  • MAGE-E1
• GenBank acession
  • AF320908
• Locus
  Xp11.22
• Discovery year
  2003-12-23
• Entrez gene record
  728239
• Pubmed identfication
  • 11406556
• RefSeq identity
  • NM_001098800
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000042235

Gene info

• Identity
  HGNC:16353
• Gene
  MAGED2
• Long gene name
  MAGE family member D2
• Synonyms gene name
  • melanoma antigen family D2
• Synonyms
  • JCL-1
  • BCG1
  • 11B6
  • MAGE-D2
  • HCA10
  • MAGED
  • MGC8386
• Synonyms name
  • hepatocellular carcinoma associated protein
  • breast cancer associated gene 1
  • melanoma-associated antigen D2
  • hepatocellular carcinoma-associated protein HCA10
• GenBank acession
  • AF128527
• Locus
  Xp11.21
• Discovery year
  2001-08-16
• Entrez gene record
  10916
• RefSeq identity
  • NM_014599
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021638
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6796
• Gene
  MAGEA1
• Long gene name
  MAGE family member A1
• Synonyms gene
  • MAGE1
• Synonyms gene name
  • melanoma antigen family A, 1 (directs expression of antigen MZ2-E)
  • melanoma antigen family A1
• Synonyms
  • MGC9326
  • CT1.1
• Synonyms name
  • melanoma-associated antigen 1
  • melanoma-associated antigen MZ2-E
  • melanoma antigen MAGE-1
  • melanoma antigen family A 1
  • cancer/testis antigen family 1, member 1
• Locus
  Xq28
• Discovery year
  1994-04-04
• Entrez gene record
  4100
• Pubmed identfication
  • 1840703
  • 25590999
• RefSeq identity
  • NM_004988
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000024192
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6802
• Gene
  MAGEA4
• Long gene name
  MAGE family member A4
• Synonyms gene
  • MAGE4
• Synonyms gene name
  • melanoma antigen family A4
• Synonyms
  • MAGE4A
  • MAGE4B
  • MAGE-41
  • MAGE-X2
  • MGC21336
  • CT1.4
• Synonyms name
  • melanoma-associated antigen 4
  • cancer/testis antigen family 1, member 4
• Locus
  Xq28
• Discovery year
  1994-04-04
• Entrez gene record
  4103
• Pubmed identfication
  • 8575766
• RefSeq identity
  • NM_002362
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000024174
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:12326
• Gene
  TRO
• Long gene name
  trophinin
• Synonyms
  • MAGE-D3
  • KIAA1114
  • MAGED3
• GenBank acession
  • U04811
• Locus
  Xp11.21
• Discovery year
  1997-10-30
• Entrez gene record
  7216
• Pubmed identfication
  • 9533028
  • 11454705
• RefSeq identity
  • NM_016157
• Classification
  • MAGE family
  • Small nucleolar RNA protein coding host genes
• VEGA ID
  OTTHUMG00000021640
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23795
• Gene
  MAGEB5
• Long gene name
  MAGE family member B5
• Synonyms gene name
  • melanoma antigen family B5
• Synonyms
  • MAGE-B5
  • CT3.3
• Synonyms name
  • cancer/testis antigen family 3, member 3
• GenBank acession
  • AF333705
• Locus
  Xp21.3
• Discovery year
  2003-12-10
• Entrez gene record
  347541
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_001271752
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021288
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:13574
• Gene
  MAGEC2
• Long gene name
  MAGE family member C2
• Synonyms gene
  • MAGEE1
• Synonyms gene name
  • melanoma antigen, family E, 1, cancer/testis specific
  • melanoma antigen family C2
• Synonyms
  • CT10
  • MAGE-C2
  • HCA587
• Synonyms name
  • cancer/testis antigen 10
• GenBank acession
  • AF116195
• Locus
  Xq27.2
• Discovery year
  2000-09-26
• Entrez gene record
  51438
• Pubmed identfication
  • 10699956
  • 20864041
• RefSeq identity
  • NM_016249
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022574
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23796
• Gene
  MAGEB6
• Long gene name
  MAGE family member B6
• Synonyms gene name
  • melanoma antigen family B6
• Synonyms
  • FLJ40242
  • MAGE-B6
  • MAGEB6A
  • CT3.4
• Synonyms name
  • cancer/testis antigen family 3, member 4
• GenBank acession
  • AF320514
• Locus
  Xp21.3
• Discovery year
  2003-12-10
• Entrez gene record
  158809
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_173523
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021285
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:23798
• Gene
  MAGEC3
• Long gene name
  MAGE family member C3
• Synonyms gene name
  • melanoma antigen family C3
• Synonyms
  • HCA2
  • MAGE-C3
  • CT7.2
• Synonyms name
  • cancer/testis antigen family 7, member 2
• GenBank acession
  • AF490508
• Locus
  Xq27.2
• Discovery year
  2003-12-10
• Entrez gene record
  139081
• Pubmed identfication
  • 10861452
• RefSeq identity
  • NM_138702
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000022570
• Locus Specific Databases
  • Global Variome shared LOVD

Gene info

• Identity
  HGNC:6809
• Gene
  MAGEB2
• Long gene name
  MAGE family member B2
• Synonyms gene name
  • melanoma antigen family B2
• Synonyms
  • DAM6
  • MAGE-XP-2
  • MGC26438
  • CT3.2
• Synonyms name
  • DSS/AHC critical interval MAGE superfamily 6
  • melanoma-associated antigen B2
  • cancer/testis antigen family 3, member 2
• GenBank acession
  • AF015766
• Locus
  Xp21.2
• Discovery year
  1997-08-15
• Entrez gene record
  4113
• Pubmed identfication
  • 9441743
• RefSeq identity
  • NM_002364
• Classification
  • MAGE family
• VEGA ID
  OTTHUMG00000021319
• Locus Specific Databases
  • Global Variome shared LOVD

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

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