LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 647

• Catalog number
  bs-6070R-A647
• Price
  Please ask
• Size
  100ul

• Long name
  LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 647 Conjugated
• Also known as
  Anti-LLGL1 + LLGL2 Ser650+Ser654 PAb ALEXA FLUOR 647
• Category
  Conjugated Primary Antibodies
• Conjugated with
  ALEXA FLUOR® 647
• Host Organism
  Rabbit (Oryctolagus cuniculus)
• Target Antigen
  LLGL1 + LLGL2 Ser650+Ser654
• Specificity
  This is a highly specific antibody against LLGL1 + LLGL2 Ser650+Ser654.
• Modification
  Phosphorylation
• Modification Site
  Ser650+Ser654
• Clonality
  Polyclonal
• Clone
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  KLH conjugated synthetic phosphopeptide derived from mouse LLGL1 around the phosphorylation site of Ser650+Ser654
• Gene ID Number
  3996
• Tested applications
  IF(IHC-P)
• Recommended dilutions
  IF(IHC-P)(1:50-200)
• Crossreactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the antigen
  LLGL1 is a protein that is similar to a tumor suppressor in Drosophila. The protein is part of a cytoskeletal network and is associated with nonmuscle myosin II heavy chain and a kinase that specifically phosphorylates this protein at serine residues. The gene for LLGL1 is located within the Smith-Magenis syndrome region on chromosome 17. LLGL2 is a protein similar to lethal giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells.
• Purification
  Purified by Protein A.
• Storage conditions
  Store this antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Keep refrigerated at 2 to 8 degrees Celcius for up to one year.
• Excitation emission
  650nm/665nm
• Synonyms
  LLGL1 + LLGL2 phospho S650 + S654; LLGL1 + LLGL2 phospho Ser650 + Ser654; p-LLGL1 + p-LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650 + Ser654; p-LLGL1/LLGL2 S650 + S654; p-LLGL1/LLGL2 Ser650/654; DLG4; HGL; HUGL; HUGL1; lethal giant larvae homolog 1; lethal giant larvae homolog 2; Lethal2 giant larvae protein homolog 1; Lethal2 giant larvae protein homolog 2; LGL2; LLGL; L2GL1_HUMAN; L2GL2_HUMAN.
• Properties
  For facs or microscopy Alexa 1 conjugate. Alexa Fluor 633 is a practical alternative to APC as well as Cy5. Bioss Primary Conjugated Antibodies. ALEXA FLUOR made this Alexa Fluor 633 conjugate that can be used in multi-color flow cytometry with instruments equipped with a second red laser or red diode. It is detected in the FL4 detector of the core's upgraded 2-laser FACScans. Like other Alexa Fluor dyes, the Anti-LLGL1 + LLGL2 Ser650+Ser654 exhibits uncommon photo stability, making it an ideal choice for fluorescent microscopy. If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies. ALEXA FLUOR they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• Conjugation
  Alexa Fluor, ALEXA FLUOR 647
• French translation
  anticorps

• Gene target
  LLGL1   LLGL2   Ser650+Ser654  
• Gene symbol
  LLGL2, LLGL1
• Short name
  Anti-LLGL1 + LLGL2 Ser650+Ser654
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Immunoglobulin G (IgG)
• Label
  ALEXA FLUOR 647
• Alternative name
  LLGL1 + LLGL2(Ser650+Ser654) Antibody, ALEXA FLUOR 647
• Alternative technique
  antibodies
• Alternative to gene target
  lethal giant larvae homolog 1 (Drosophila), DLG4 and HUGL and HUGL-1 and HUGL1 and LLGL, LLGL1 and IDBG-33645 and ENSG00000131899 and 3996, protein kinase binding, Cytoplasm, Llgl1 and IDBG-181336 and ENSMUSG00000020536 and 16897, LLGL1 and IDBG-638036 and ENSBTAG00000004635 and 781865

Gene info

• Identity
  HGNC:6629
• Gene
  LLGL2
• Long gene name
  LLGL scribble cell polarity complex component 2
• Synonyms gene name
  • lethal giant larvae homolog 2 (Drosophila)
  • lethal giant larvae homolog 2, scribble cell polarity complex component
  • LLGL2, scribble cell polarity complex component
• Synonyms
  • HGL
  • Hugl-2
• GenBank acession
  • X87342
• Locus
  17q25.1
• Discovery year
  1997-01-28
• Entrez gene record
  3993
• Pubmed identfication
  • 22580609
• RefSeq identity
  • NM_004524
• Classification
  • WD repeat domain containing
  • Scribble complex
• VEGA ID
  OTTHUMG00000179685

Gene info

• Identity
  HGNC:6628
• Gene
  LLGL1
• Long gene name
  LLGL scribble cell polarity complex component 1
• Synonyms gene
  • DLG4
  • LLGL
  • HUGL
  • HUGL-1
• Synonyms gene name
  • lethal giant larvae homolog 1 (Drosophila)
  • lethal giant larvae homolog 1, scribble cell polarity complex component
• Synonyms
  • Lgl1
  • Mgl1
• Locus
  17p11.2
• Discovery year
  1995-09-12
• Entrez gene record
  3996
• Pubmed identfication
  • 7542763
  • 8565641
• Classification
  • Scribble complex
  • WD repeat domain containing
• VEGA ID
  OTTHUMG00000059396

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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