Clonality Polyclonal antibody
Immunogen species Human
Antibody category Polyclonal Antibodies
Background Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
Antibody isotype IgG
Shipping and storage LIN7A Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.
Purification method Protein G purified
Format Liquid, diluted in buffer
UniProt ID O14910
Alias Protein lin-7 homolog A,Lin-7A,hLin-7,Mammalian lin-seven protein 1,MALS-1,Tax interaction protein 33,TIP-33,Vertebrate lin-7 homolog 1,Veli-1,LIN7A,MALS1,VELI1
Buffer composition Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Immunogen type Recombinant human Protein lin-7 homolog A protein (1-233AA)
Properties If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
French translation anticorps
Short name LIN7A Antibody
Alternative name lin-7 homolog A (C. elegans) (Antibody to)
Alternative technique antibodies
Alternative to gene target lin-7 homolog A (C. elegans), LIN-7A and LIN7 and MALS-1 and TIP-33 and VELI1, LIN7A and IDBG-49666 and ENSG00000111052 and 8825, L27 domain binding, Cell surfaces, Lin7a and IDBG-189088 and ENSMUSG00000019906 and 108030, LIN7A and IDBG-630389 and ENSBTAG00000011367 and 528379