LATS1/2 Antibody

• Catalog number
  bs-4081R
• Price
  Please ask
• Size
  0.1ml

• Long name
  LATS1/2 Primary Polyclonal Antibody
• Also known as
  LATS1/2 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  LATS1/2
• Specificity
  This is a highly specific antibody against LATS1/2. This antibody will detects both LATS1 and LATS2.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  640-690/1088
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human LATS2
• Gene ID number
  26524, 9113
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq].
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Serine/threonine-protein kinase LATS1; LATS1; Large tumor suppressor homolog 1; WARTS protein kinase; h-warts; WARTS; Serine/threonine-protein kinase LATS2; LATS2; Kinase phosphorylated during mitosis protein; Large tumor suppressor homolog 2; Serine/threonine-protein kinase kpm; Warts-like kinase; KPM
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  LATS1/2  
• Gene symbol
  LATS1
• Short name
  Anti-LATS1/2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  LATS1/2 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6514
• Gene
  LATS1
• Long gene name
  large tumor suppressor kinase 1
• Synonyms gene name
  • LATS (large tumor suppressor, Drosophila) homolog 1
  • LATS, large tumor suppressor, homolog 1 (Drosophila)
• Synonyms
  • WARTS
• GenBank acession
  • AF104413
• Locus
  6q25.1
• Discovery year
  1999-02-18
• Entrez gene record
  9113
• Pubmed identfication
  • 9988268
  • 15122335
• RefSeq identity
  • NM_004690
• Classification
  • AGC family kinases
• VEGA ID
  OTTHUMG00000016437

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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