Lass1 (Cross reacts with GDF1) - Blocking Peptide
-
Catalog number
X2294B
-
Price
Please ask
-
Size
50 μg
-
-
Category
Proteins & Peptides
-
Long description
LAG1 is a longevity gene, the first such gene to be identified. Originally cloned from the yeast Saccharomyces cerevisiae. A close homolog of this gene, LAC1, has been found in the yeast genome. The human homolog of LAG1 has functions in human aging. LAG1 may be involved in neurodegenerative diseases and human aging. Lass1 may be either a bona fide (dihydro)ceramide synthase or a modulator of its activity. When overexpressed in cells is involved in the production of sphingolipids containing mainly one fatty acid donor (N-linked stearoyl- (C18) ceramide) in a fumonisin B1-independent manner. Located in the endoplasmic reticulum membrane; LAss1 is a multi-pass membrane protein.
-
Antibody come from
Synthetic peptide dervied from the human FBXW7 protein
-
Other description
Provided as solution in phosphate buffered saline with 0.08% sodium azide.
-
Clone
not specified
-
Antigen antibody binding interaction
Lass1 (Cross reacts with GDF1) - Blocking Peptide
-
Antibody is raised in
see techfile
-
Antibody s reacts with
Human
-
Antibody s reacts with these species
This antibody doesn't cross react with other species
-
Antibody s specificity
No Data Available
-
Application
Western Blot
-
Antibody s suited for
Antibody can be used for Western blotting (1:400 starting dilution). Optimal concentration should be evaluated by serial dilutions.
-
Storage
-20ºC
-
Relevant references
1. Strohmaier, H., et al. 'Human F-box protein hCdc4 targets cyclin E for proteolysis and is mutated in a breast cancer cell line.; Nature 413:316-322(2001)._x000B__x000B_2. Moberg, K.H., et al. 'Archipelago regulates cyclin E levels in Drosophila and is mutated in human cancer cell lines.; Nature 413:311-316(2001).
-
Protein number
see ncbi
-
Warnings
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
-
-
Test
You can block the antibody by the specific target amino acid sequence of peptide.
-
Properties
blocking peptide
-
Description
Peptides short amino acid chains or epitopes or blocking antagonists. The shortest peptides are dipeptides, consisting of 2 amino acids joined by a single peptide bond, followed by tripeptides, tetra peptides, ... till polypeptides that are long, continuous, and unbranched synthetic peptide chains. These biological oligomers and polymers can be Solid-phase peptide synthesis (SPPS), or in continue produced for custom peptide synthesis projects. The High-efficiency solid phase peptide synthesis (HE-SPPS) is give very low production costs.
-
Gene target
-
Gene symbol
GDF1
-
Short name
Lass1 (Cross reacts with GDF1) - Blocking Peptide
-
Technique
blocking peptide, Blocking, peptide, blocking peptides, nordc made this blocking amino acid sequence or peptide to block the gene target in a volume of 1. For western blot it is often requested to block your antibody and to see the band of the analyzed protein disappear. This is called a negative control by blocking the WB antibody. peptides
-
Isotype
not specified
-
Label
unlabeled
-
Alternative name
Lass1 (Cross reacts including growth differentiation factor 1) - inhibiting short protein sequence
-
Alternative technique
control, peptides
-
Alternative to gene target
growth differentiation factor 1, GDF1 and IDBG-38953 and ENSG00000130283 and 2657, growth factor activity, Extracellular, Gdf1 and IDBG-162564 and ENSMUSG00000055694 and 14559, BT.45969 and IDBG-641581 and ENSBTAG00000020923 and 615296
-
Gene info
Similar products
