Laminin Antibody (Gamma)

• Catalog number
  R31563
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  Laminin (Gamma)
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB, IHC-P, ICC
• Recommended dilutions
  Western blot: 0.5-1ug/ml,IHC (Paraffin): 0.5-1ug/ml,Immunocytochemistry: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting points. Titration of the Laminin antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This Laminin antibodyis to be used only for research purposes and not for diagnostics..
• Gene ID
  3915, 3918, 10319
• Purity
  Antigen affinity
• Description
  Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins form independent networks and are associated with type IV collagen networks via entactin, fibronectin, and perlecan. They are important and biologically active parts of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. Laminins are trimeric proteins that contain an alpha-chain, a beta-chain, and a gamma-chain, found in five, four, and three genetic variants, respectively. Laminins critically contribute to cell attachment and differentiation, cell shape and movement, maintenance of tissue phenotype, and promotion of tissue survival.
• Immunogen
  A peptide mixture of Laminin gamma 1, 2 & 3 (DLNKLNEIEGTLNKAKDEMK + MSELEERARQQRGHLHLLET + LQRKLSLLEQESQQQELQIQ) was used as the immunogen for this Laminin antibody.
• Storage
  After reconstitution, the Laminin antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  Laminin   Gamma  
• Gene symbol
  LAMC3, LAMC1, LAMC2
• Short name
  Anti-Laminin (Gamma)
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to Laminin (Gamma)
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6494
• Gene
  LAMC3
• Long gene name
  laminin subunit gamma 3
• Synonyms gene name
  • laminin, gamma 3
• Synonyms
  • DKFZp434E202
• GenBank acession
  • AF041835
• Locus
  9q34.12
• Discovery year
  1999-07-23
• Entrez gene record
  10319
• Pubmed identfication
  • 10225960
• RefSeq identity
  • NM_006059
• Classification
  • Laminin subunits
• VEGA ID
  OTTHUMG00000020819

Gene info

• Identity
  HGNC:6492
• Gene
  LAMC1
• Long gene name
  laminin subunit gamma 1
• Synonyms gene
  • LAMB2
• Synonyms gene name
  • laminin, gamma 1 (formerly LAMB2)
• GenBank acession
  • J03202
• Locus
  1q25.3
• Discovery year
  2001-06-22
• Entrez gene record
  3915
• Pubmed identfication
  • 3234037
• RefSeq identity
  • NM_002293
• Classification
  • Laminin subunits
• VEGA ID
  OTTHUMG00000035418

Gene info

• Identity
  HGNC:6493
• Gene
  LAMC2
• Long gene name
  laminin subunit gamma 2
• Synonyms gene
  • EBR2
  • LAMB2T
  • LAMNB2
  • EBR2A
• Synonyms gene name
  • laminin, gamma 2 (nicein (100kD), kalinin (105kD), BM600 (100kD), Herlitz junctional epidermolysis bullosa))
  • laminin, gamma 2
• Synonyms
  • nicein-100kDa
  • kalinin-105kDa
  • BM600-100kDa
• GenBank acession
  • Z15008
• Locus
  1q25.3
• Discovery year
  1993-07-13
• Entrez gene record
  3918
• Pubmed identfication
  • 1383240
• RefSeq identity
  • NM_005562
• Classification
  • Laminin subunits
• VEGA ID
  OTTHUMG00000035520

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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