KLK6 Antibody

• Catalog number
  bs-5870R
• Price
  Please ask
• Size
  0.1ml

• Long name
  KLK6 Primary Polyclonal Antibody
• Also known as
  KLK6 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  KLK6
• Specificity
  This is a highly specific antibody against KLK6.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  200-240/244
• Subcellular location
  Cytoplasm, Nucleus, Secreted, Mitochondrion
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLK6
• Gene ID number
  5653
• Swiss Prot
  Q92876
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Serine protease which exhibits a preference for Arg over Lys in the substrate P1 position and for Ser or Pro in the P2 position. Shows activity against amyloid precursor protein, myelin basic protein, gelatin, casein and extracellular matrix proteins such as fibronectin, laminin, vitronectin and collagen. Degrades alpha-synuclein and prevents its polymerization, indicating that it may be involved in the pathogenesis of Parkinson disease and other synucleinopathies. May be involved in regulation of axon outgrowth following spinal cord injury. Tumor cells treated with a neutralizing KLK6 antibody migrate less than control cells, suggesting a role in invasion and metastasis.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  hK6; Bssp; Klk7; SP59; PRSS9; PRSS18; Kallikrein-6; Neurosin; Protease M; Serine protease 18; Serine protease 9; Zyme; KLK6
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KLK6  
• Gene symbol
  KLK1, KLK6
• Short name
  Anti-KLK6
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  KLK6 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:6357
• Gene
  KLK1
• Long gene name
  kallikrein 1
• Synonyms gene name
  • kallikrein 1, renal/pancreas/salivary
• Synonyms
  • Klk6
• GenBank acession
  • L10038
• Locus
  19q13.33
• Discovery year
  1988-06-27
• Entrez gene record
  3816
• Pubmed identfication
  • 1684954
  • 16800724
  • 16800723
• RefSeq identity
  • NM_002257
• Classification
  • Kallikreins
• VEGA ID
  OTTHUMG00000182876

Gene info

• Identity
  HGNC:6367
• Gene
  KLK6
• Long gene name
  kallikrein related peptidase 6
• Synonyms gene
  • PRSS9
  • PRSS18
• Synonyms gene name
  • protease, serine, 18
  • kallikrein 6 (neurosin, zyme)
• Synonyms
  • Bssp
  • Klk7
  • neurosin
• GenBank acession
  • U62801
• Locus
  19q13.41
• Discovery year
  1997-06-09
• Entrez gene record
  5653
• Pubmed identfication
  • 9003450
  • 16800724
  • 16800723
• RefSeq identity
  • NM_002774
• Classification
  • Kallikreins
  • Serine proteases
• VEGA ID
  OTTHUMG00000183098

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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