KLHL25 Antibody

• Catalog number
  bs-8051R
• Price
  Please ask
• Size
  0.1ml

• Long name
  KLHL25 Primary Polyclonal Antibody
• Also known as
  KLHL25 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  KLHL25
• Specificity
  This is a highly specific antibody against KLHL25.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  435-485/589
• Subcellular location
  Intracellular
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human KLHL25
• Gene ID number
  64410
• Swiss Prot
  Q9H0H3
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  ENC2; ENC-2; Kelch-like protein 25; Ectoderm-neural cortex protein 2; KLHL25
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KLHL25  
• Gene symbol
  KLHL25
• Short name
  Anti-KLHL25
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  KLHL25 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:25732
• Gene
  KLHL25
• Long gene name
  kelch like family member 25
• Synonyms gene name
  • kelch-like 25 (Drosophila)
• Synonyms
  • FLJ12587
  • ENC2
  • ENC-2
• Synonyms name
  • ectodermal-neural cortex 2
• Locus
  15q25.3
• Discovery year
  2005-11-17
• Entrez gene record
  64410
• RefSeq identity
  • NM_022480
• Classification
  • BTB domain containing
  • Kelch like
  • MicroRNA protein coding host genes
• VEGA ID
  OTTHUMG00000148672

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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