KCNQ2 Antibody

• Catalog number
  R31423
• Price
  Please ask
• Size
  0.1mg

• Category
  Antibody
• Concentration
  0.5mg/ml if reconstituted with 0.2ml sterile DI water
• Form
  Antigen affinity purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  KCNQ2
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus), Rat ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  WB
• Recommended dilutions
  Western blot: 0.5-1ug/ml
• Notes
  The stated application concentrations are suggested starting amounts. Titration of the KCNQ2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This KCNQ2 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  O43526
• Purity
  Antigen affinity
• Description
  KCNQ2, also called Kv7.2, is a potassium channel protein coded for by the gene KCNQ2. It is mapped to 20q13.33. The gene encodes a voltage-gated potassium channel that is expressed in the brain. Expression of human KCNQ2 in Xenopus laevis oocytes led to potassium-selective currents that activated slowly with depolarization. Defects in this gene are a cause of benign familial neonatal convulsions type 1(BFNC), also known as epilepsy, benign neonatal type 1(EBN1). At least five transcript variants encoding five different isoforms have been found for this gene.
• Immunogen
  An amino acid sequence from the N-terminus of human KCNQ2 (DLHSTWQYYERTVTVPMY) was used as the immunogen for this KCNQ2 antibody.
• Storage
  After reconstitution, the KCNQ2 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized. Avoid repeated freezing and thawing.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  KCNQ2  
• Gene symbol
  KCNQ2-AS1, KCNQ2
• Short name
  Anti-KCNQ2
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit IgG
• Alternative name
  Antibodies to KCNQ2
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:40321
• Gene
  KCNQ2-AS1
• Long gene name
  KCNQ2 antisense RNA 1
• Locus
  20q13.33
• Discovery year
  2019-08-15
• Entrez gene record
  105372720
• Classification
  • Antisense RNAs

Gene info

• Identity
  HGNC:6296
• Gene
  KCNQ2
• Long gene name
  potassium voltage-gated channel subfamily Q member 2
• Synonyms gene
  • EBN
  • EBN1
• Synonyms gene name
  • potassium voltage-gated channel, KQT-like subfamily, member 2
  • potassium channel, voltage gated KQT-like subfamily Q, member 2
• Synonyms
  • Kv7.2
  • ENB1
  • BFNC
  • KCNA11
  • HNSPC
• GenBank acession
  • AF033348
• Locus
  20q13.33
• Discovery year
  1998-01-12
• Entrez gene record
  3785
• Pubmed identfication
  • 9425895
  • 16382104
• RefSeq identity
  • NM_172109
• Classification
  • Potassium voltage-gated channels
• VEGA ID
  OTTHUMG00000033049

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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