JMY Antibody

• Catalog number
  bs-7614R
• Price
  Please ask
• Size
  0.1ml

• Long name
  JMY Primary Polyclonal Antibody
• Also known as
  JMY PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  JMY
• Specificity
  This is a highly specific antibody against JMY.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  445-475/988
• Subcellular location
  Cytoplasm, Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human JMY
• Gene ID number
  133746
• Swiss Prot
  Q8N9B5
• Tested Applications
  IHC-P, IF(IHC-P)
• Recommended dilutions
  IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Acts both as a nuclear p53/TP53-cofactor and a cytoplasmic regulator of actin dynamics depending on conditions. In nucleus, acts as a cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependent transcription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage. In cytoplasm, acts as a nucleation-promoting factor for both branched and unbranched actin filaments. Activates the Arp2/3 complex to induce branched actin filament networks. Also catalyzes actin polymerization in the absence of Arp2/3, creating unbranched filaments. Contributes to cell motility by controlling actin dynamics. May promote the rapid formation of a branched actin network by first nucleating new mother filaments and then activating Arp2/3 to branch off these filaments. The p53/TP53-cofactor and actin activator activities are regulated via its subcellular location (By similarity).
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  WHAMM2; WHDC1L3; Junction-mediating and -regulatory protein; JMY
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  JMY  
• Gene symbol
  JMY
• Short name
  Anti-JMY
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  JMY Polyclonal Antibody
• Alternative technique
  antibodies
• Alternative to gene target
  junction mediating and regulatory protein, p53 cofactor, JMY and IDBG-30979 and ENSG00000152409 and 133746, protein binding, nuclei, Jmy and IDBG-172833 and ENSMUSG00000021690 and 57748, JMY and IDBG-645239 and ENSBTAG00000025856 and 101909783,528498

Gene info

• Identity
  HGNC:28916
• Gene
  JMY
• Long gene name
  junction mediating and regulatory protein, p53 cofactor
• Synonyms
  • FLJ37870
  • WHAMM2
• GenBank acession
  • AK095189
• Locus
  5q14.1
• Discovery year
  2009-02-06
• Entrez gene record
  133746
• Pubmed identfication
  • 10518217
  • 22316129
• RefSeq identity
  • NM_152405
• Classification
  • Wiskott-Aldrich Syndrome protein family
• VEGA ID
  OTTHUMG00000131301

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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