Ipragliflozin
#
-
Catalog numberB1926-25
-
Price:
-
Size25 mg
-
-
Alternative_name(2S,3R,4R,5S,6R)-2-[3-(1-benzothiophen-2-ylmethyl)-4-fluorophenyl]-6-(hydroxymethyl)oxane-3,4,5-triol
-
DescriptionIpragliflozin is a potent inhibitor of sodium-glucose cotransporter 2 (SGLT2; IC₅₀ = 7.4 nM for human SGLT2 in vitro) that increases excretion of glucose.Iipragliflozin is found to promote preferential loss of fat mass in a rat model of non-obese type 2 diabetes mellitus (T2DM).
-
CAS Number761423-87-4
-
Structure AvailableYes
-
Salt FormNo
-
Molecular FormulaC₂₁H₂₁FO₅S
-
Molecular Weight404.45
-
Cell PermeableYes
-
Purity≥98% by HPLC
-
SolubilitiesDMSO (~30 mg/ml)
-
HandlingProtect from air and light
-
Tag LineA potent sodium-glucose cotransporter 2 (SGLT2) inhibitor
-
Storage Condition-20°C
-
Shipping Conditiongel pack
-
Shelf Life36 months
-
PubChem CID10453870
-
SMILESC1=CC=C2C(=C1)C=C(S2)CC3=C(C=CC(=C3)C4C(C(C(C(O4)CO)O)O)O)F
-
InChiInChI=1S/C21H21FO5S/c22-15-6-5-12(21-20(26)19(25)18(24)16(10-23)27-21)7-13(15)9-14-8-11-3-1-2-4-17(11)28-14/h1-8,16,18-21,23-26H,9-10H2/t16-,18-,19+,20-,21+/m1/s1
-
InChi KeyAHFWIQIYAXSLBA-RQXATKFSSA-N
-
MSDS AvailableYes
-
Gene target
-
Short nameIpragliflozin
-
Alternative nameIpragliflozin
-