INTS3 Antibody

• Catalog number
  bs-9766R
• Price
  Please ask
• Size
  0.1ml

• Long name
  INTS3 Primary Polyclonal Antibody
• Also known as
  INTS3 PAb
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  INTS3
• Specificity
  This is a highly specific antibody against INTS3.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Immunogen range
  960-998/1043
• Subcellular location
  Nucleus
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human INTS3
• Gene ID number
  65123
• Swiss Prot
  Q68E01
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  INT3; SOSSA; SOSS-A; C1orf60; C1orf193; Integrator complex subunit 3; SOSS complex subunit A; Sensor of single-strand DNA complex subunit A; Sensor of ssDNA subunit A; INTS3
• Properties
  If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  INTS3  
• Gene symbol
  INTS3
• Short name
  Anti-INTS3
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  INTS3 Polyclonal Antibody
• Alternative technique
  antibodies

Gene info

• Identity
  HGNC:26153
• Gene
  INTS3
• Long gene name
  integrator complex subunit 3
• Synonyms gene
  • C1orf60
• Synonyms gene name
  • chromosome 1 open reading frame 60
• Synonyms
  • FLJ21919
  • INT3
  • SOSS-A
• Synonyms name
  • sensor of single-strand DNA complex subunit A
• GenBank acession
  • BX640950
• Locus
  1q21.3
• Discovery year
  2005-05-13
• Entrez gene record
  65123
• Pubmed identfication
  • 16239144
• RefSeq identity
  • NM_023015
• Classification
  • Integrator complex
• VEGA ID
  OTTHUMG00000037089

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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