IL1RAP Antibody
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Catalog numberbs-18144R
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Price:
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Size0.1ml
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Long nameIL1RAP Primary Polyclonal Antibody
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Also known asIL1RAP PAb
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CategoryPrimary Antibodies
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ConjugationUnconjugated
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Target AntigenIL1RAP
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SpecificityThis is a highly specific antibody against IL1RAP.
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Modification sNone
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Modification site sUnmodified antibody
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ClonalityPolyclonal antibody
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Clone numberPolyclonal antibody
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Concentration1ug per 1ul
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Immunogen range300-335/570
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Subcellular locationExtracellular
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SourceThis antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human IL1RAP/IL1R3
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Gene ID number3556
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Swiss ProtQ9NPH3
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Tested ApplicationsWB
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Recommended dilutionsWB(1:100-1000)
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Cross reactivityHuman, Mouse, Rat
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Cross reactive species detailsDue to limited amount of testing and knowledge, not every possible cross-reactivity is known.
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Background of the target antigenCoreceptor for IL1RL2 in the IL-36 signaling system (By similarity). Coreceptor with IL1R1 in the IL-1 signaling system. Associates with IL1R1 bound to IL1B to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Recruits TOLLIP to the signaling complex. Does not bind to interleukin-1 alone; binding of IL1RN to IL1R1, prevents its association with IL1R1 to form a signaling complex. The cellular response is modulated through a non-signaling association with the membrane IL1R2 decoy receptor. Secreted forms (isoforms 2 and 3) associate with secreted ligand-bound IL1R2 and increase the affinity of secreted IL1R2 for IL1B; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.
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Purification methodThis antibody was purified via Protein A.
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Storage conditionsKeep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
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Synonym namesIL1R3; C3orf13; IL-1RAcP; Interleukin-1 receptor accessory protein; IL-1 receptor accessory protein; Interleukin-1 receptor 3; IL-1R-3; IL-1R3; IL1RAP
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PropertiesIf you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
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French translationanticorps
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Gene target
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Gene symbolIL1RAP
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Short nameAnti-IL1RAP
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TechniqueAntibody, antibodies against human proteins, antibodies for
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HostRabbit (Oryctolagus cuniculus)
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IsotypeImmunoglobulin G (IgG)
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Alternative nameIL1RAP Polyclonal Antibody
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Alternative techniqueantibodies
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Alternative to gene targetinterleukin 1 receptor accessory protein, C3orf13 and IL-1RAcP and IL1R3, IL1RAP and IDBG-69682 and ENSG00000196083 and 3556, protein binding, Extracellular, Il1rap and IDBG-150439 and ENSMUSG00000022514 and 16180, IL1RAP and IDBG-634437 and ENSBTAG00000013205 and 539334
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Gene info
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Identity
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Gene
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Long gene nameinterleukin 1 receptor accessory protein
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Synonyms
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GenBank acession
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Locus
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Discovery year1997-10-09
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Interleukin receptors
- TIR domain containing
- Immunoglobulin like domain containing
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VEGA ID
MeSH Data
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Name
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ConceptScope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
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Tree numbers
- E05.196.401.143
- E05.301.300.096
- E05.478.566.320.200
- E05.601.262
- E05.601.470.320.200
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data