D-Serine Dehydratase, Active, Recombinant

  • Catalog number
    P1193-200
  • Price
    Please ask
  • Size
    200 ug
  • Synonyms
    DsdSC, D-serine deaminase, DSD, DSD1
  • Alternative_names
    DsdSC, D-serine deaminase, DSD, DSD1
  • Description
    Converts D-serine to pyruvate and ammonia
  • Recombinant
    Yes
  • Source
    E.coli
  • Purity by SDS PAGE
    > 95%
  • Assay
    SDS-PAGE
  • Activity Specifications test method
    Measured by its ability to metabolizes 1 umole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
  • Biological activity
    Specific activity is ≥ 60 mU/mg
  • Results
    ≥ 60 mU/mg
  • Unit Definition
    One Unit of DsdSC metabolizes 1 umole of D-serine into pyruvate per minute at 37°C and pH 7.4, in the presence of pyridoxal-5-phosphate and catalytic Zn2+.
  • Molecular Weight
    47.8 kDa
  • Storage Temp
    -20°C
  • Shipping
    Gel Pack
  • Shelf Life
    12 months
  • Appearance
    Lyophilized
  • Physical form description
    Lyophilized from 50 mM Sodium phosphate, pH 7.0, 30% glycerol
  • Reconstitution Instructions
    Reconstitute in 50 mM potassium phosphate, 50 mM NaCl, pH 7.4.
  • Background Information
    D-Serine Dehydratase belongs to the β- family of the Pyridoxal phosphate-dependent enzymes and part of the fold-type II family. It binds to one catalytically essential PLP per protein molecule but also contains another low affinity PLP binding site. The enzyme converts D-Serine, D-threonine, D-allo-Threonine to corresponding α-keto acid and ammonia. It is suggested to act as a detoxifying enzyme for E.Coli strains.
  • Handling
    Centrifuge the vial prior to opening.
  • Usage
    For Research Use Only! Not to be used in humans
  • Additional source
    Recombinants or rec. proteins
  • Group
    recombinants
  • Additional description
    Serine protease, D- or L-serine arginine rich enzyme of serine threonine kinase with serine that is encoded by the codons UCU, UCC, UCA, UCG, AGU and AGC is an ɑ-amino acid that is used in the biosynthesis of proteins. It contains an α-amino group (which is in the protonated −NH+ 3 form under biological conditions), a carboxyl group. It is non-essential in humans, meaning the body can synthesize it.
  • Gene target
  • Short name
    D-Serine Dehydratase, Active, Recombinant
  • Technique
    Recombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
  • Alternative name
    D-Serine Dehydratase, functionnal, Rec.
  • Alternative technique
    rec
MeSH Data
  • Name
  • Concept
    Scope note: The initial culturing of cells derived directly from fresh TISSUES.
  • Tree numbers
    • E01.370.225.500.223.500
    • E05.200.500.265.500
    • E05.242.223.500
    • E05.481.500.249.500
  • Qualifiers
    ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data
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