Human CellExp™ NOV, human recombinant
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Catalog numberP1022-25
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PricePlease ask
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Size25 µg
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SynonymsNephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
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Alternative_namesNephroblastoma Overexpressed gene, CCN3, IGFBP9, NovH
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RecombinantYes
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SourceCHO cells
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Purity by SDS PAGE> 95%
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AssaySDS-PAGE
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Purity> 95%
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Endotoxin Level< 0.2 EU/ug
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Activity Specifications test methodProlifiration assay
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Biological activityED50
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Molecular Weight20-50 kDa
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Storage Temp-20°C
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ShippingGel pack
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Shelf Life12 months
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AppearanceLyophilized
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Physical form descriptionLyophilized after extensive dialysis against PBS.
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Reconstitution InstructionsReconstituted in ddH2O at 100 ug/mL.
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Background InformationNephroblastoma Overexpressed Gene Protein (NOV), also known as CCN3, IGFBP9 and NOVH, is one of the CCN family of secreted proteins. It is expressed in bone marrow, thymic cells and nephroblastoma. NOV signals through integrin receptors, NOTCH1 and fibulin 1c to regulate multiple cellular activities, such as cell adhesion, migration, proliferation and differentiation. The reported functions of NOV are diverse. It has been reported to play a role in angiogenesis and stem cell self-renewal. It has also been implicated in osteogenic differentiation, embryo development and cancer pathogenesis.
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Amino acid sequenceTQRCPPQCPG RCPATPPTCA PGVRAVLDGC SCCLVCARQR GESCSDLEPC DESSGLYCDR SADPSNQTGI CTAVEGDNCV FDGVIYRSGE KFQPSCKFQC TCRDGQIGCV PRCQLDVLLP EPNCPAPRKV EVPGECCEKW ICGPDEEDSL GGLTLAAYRP EATLGVEVSD SSVNCIEQTT EWTACSKSCG MGFSTRVTNR NRQCEMLKQT RLCMVRPCEQ EPEQPTDKKG KKCLRTKKSL KAIHLQFKNC TSLHTYKPRF CGVCSDGRCC TPHNTKTIQA EFQCSPGQIV KKPVMVIGTC TCHTNCPKNN EAFLQELELK TTRGKM
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HandlingCentrifuge the vial prior to opening.
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UsageFor Research Use Only! Not to be used in humans
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PropertiesHuman proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.
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Additional sourceRecombinants or rec. proteins
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Grouprecombinants
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Gene target
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Gene symbolCCN3, PLXNA1, RPL10
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Short nameCellExp™ NOV, recombinant
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TechniqueRecombinant, E. coli recombinant proteins are genetic recombinations in Escherichia coli, supplied as white sterile powder lyopillized. Biovision advises they will be reconstituted in a buffer soluion or culture medium for cell culture.
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SpeciesHumans
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Alternative nameH. sapiens CellExp™ NOV, H. sapiens Rec.
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Alternative techniquerec
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Gene info
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Identity
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Gene
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Long gene namecellular communication network factor 3
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Synonyms gene
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Synonyms gene name
- nephroblastoma overexpressed gene
- nephroblastoma overexpressed
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Synonyms
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GenBank acession
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Locus
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Discovery year1993-11-05
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Cellular communication network factors
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameplexin A1
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Synonyms gene
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-08-13
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Plexins
- IPT domain containing
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VEGA ID
Gene info
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Identity
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Gene
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Long gene nameribosomal protein L10
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Synonyms
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GenBank acession
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Locus
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Discovery year1998-07-23
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Entrez gene record
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Pubmed identfication
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RefSeq identity
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Classification
- Small nucleolar RNA protein coding host genes
- L ribosomal proteins
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VEGA ID
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Locus Specific Databases
MeSH Data
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Name
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ConceptScope note: The initial culturing of cells derived directly from fresh TISSUES.
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Tree numbers
- E01.370.225.500.223.500
- E05.200.500.265.500
- E05.242.223.500
- E05.481.500.249.500
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Qualifiersethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data