HSF1 Antibody

• Catalog number
  F48065-0.4ML
• Price
  Please ask
• Size
  0.4 ml

• Category
  Antibody
• Concentration
  In 1X PBS, pH 7.4, with 0.09% sodium azide
• Form
  Purified
• Conjugation
  Unconjugated
• Clone
  Polyclonal antibody
• Recognised antigen
  HSF1
• Host animal
  Rabbit (Oryctolagus cuniculus)
• Clonality
  Polyclonal (rabbit origin)
• Species reactivity
  Human (Homo sapiens), Mouse (Mus musculus) ; Due to limited knowledge and inability to test the antibody against all known species, we cannot guarantee that no other cross reactivity can occur.
• Tested applications
  IF, ELISA
• Recommended dilutions
  Immunofluorescence: 1:10-1:50
• Notes
  Titration of the HSF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.
• Intented use
  This HSF1 antibodyis to be used only for research purposes and not for diagnostics..
• Uniprot
  Q00613
• Purity
  Purified
• Description
  Heat shock transcription factor 1 (HSF1) mediates the induction of heat shock protein gene expression in cells exposed to elevated temperature and other stress conditions. In response to stress, HSF1 acquires DNA-binding ability and localizes to nuclear stress granules. SUMO modification of HSF1 converts HSF1 to the DNA-binding form. HSF1 colocalizes with SUMO-1 in nuclear stress granules, which is prevented by mutation of the HSF1 lysine targeted for sumoylation.
• Immunogen
  A portion of amino acids 278-309 from the human protein (sumoylation site) was used as the immunogen for this HSF1 antibody.
• Storage
  Aliquot the HSF1 antibody and store frozen at -20 deg. Celcius or lower. Cycles of freezing and thawing can denaturate the peptide chains of the antibodies and reduce their sensitivity and/or change their affinity. Prepare aliqotes in such a manner so that freeze-thaw cycles are minimized.
• Properties
  If you buy Antibodies supplied by NJS poly they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
• French translation
  anticorps

• Gene target
  HSF1  
• Gene symbol
  HSF1
• Short name
  Anti-HSF1
• Technique
  Antibody, antibodies against human proteins, antibodies for
• Isotype
  Rabbit Ig
• Alternative name
  Antibodies to HSF1
• Alternative technique
  antibodies
• Alternative to gene target
  heat shock transcription factor 1, HSTF1, HSF1 and IDBG-40498 and ENSG00000185122 and 3297, sequence-specific DNA binding, nuclei, Hsf1 and IDBG-155311 and ENSMUSG00000022556 and 15499, HSF1 and IDBG-643592 and ENSBTAG00000020751 and 506235

Gene info

• Identity
  HGNC:5224
• Gene
  HSF1
• Long gene name
  heat shock transcription factor 1
• Synonyms
  • HSTF1
• GenBank acession
  • M64673
• Locus
  8q24.3
• Discovery year
  1994-09-12
• Entrez gene record
  3297
• Pubmed identfication
  • 1871105
• RefSeq identity
  • NM_005526
• VEGA ID
  OTTHUMG00000174604

MeSH Data

• Name
  Blotting, Western
• Concept
  Scope note: Identification of proteins or peptides that have been electrophoretically separated by blot transferring from the electrophoresis gel to strips of nitrocellulose paper, followed by labeling with antibody probes.
• Tree numbers
  • E05.196.401.143
  • E05.301.300.096
  • E05.478.566.320.200
  • E05.601.262
  • E05.601.470.320.200
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

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