Mouse Anti-Chicken MHC Class II-FITC

#

• Catalog number
  GEN673934
• Price:

  559.99 USD

  Ask for price
• Size
  500ug

# #

• Also known as
  MHC Class II
• Other names
  MHC class II; MHC class II HLA-DQ-beta-1; HLA class II histocompatibility antigen, DQ beta 1 chain; MHC DQ beta; MHC class2 antigen; OTTHUMP00000029167; OTTHUMP00000178569; OTTHUMP00000178570; OTTHUMP00000178571; lymphocyte antigen; MHC class II antigen DQB1; MHC class II DQ beta chain; MHC class II antigen HLA-DQ-beta-1; MHC class II HLA-DQ beta glycoprotein; major histocompatibility complex class II beta; HLA class II histocompatibility antigen, DQ beta 1 chain-like; major histocompatibility complex, class II, DQ beta 1; N/A
• Category
  Secondary Antibodies
• Subcategory
  Mnoclonal antibodies
• Gene name
  HLA-DQB1; HLA-DQB1; IDDM1; CELIAC1; HLA-DQB; N/A
• Gene name synonims
  HLA-DQB1; HLA-DQB1; IDDM1; CELIAC1; HLA-DQB; N/A
• Other gene names
  HLA-DQB1; HLA-DQB1; IDDM1; CELIAC1; HLA-DQB; N/A
• Clonality
  Monoclonal
• Immunoglobulin isotype
  Mouse IgG1 kappa
• Clone
  2G11
• Host organism
  Mouse (Mus musculus)
• Species reactivity
  Chicken; Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
• Specificity and cross reactivity
  Chicken MHC Class II (B-L) molecules The chicken major histocompatibility complex (MHC), or B complex, consists of several clusters of highly polymorphic genes. Like their mammalian counterparts, the avian MHC exerts genetic influence over a variety of important biological functions such as immune response, disease resistance, growth and development, aging, and reproduction. Chicken MHC Class II genes, also known as the B-L subregion, of the chicken MHC encode cell surface glycoproteins that are homologous to mammalian Class II antigens. B-L antigens structurally are similar to mammalian Class II molecules in that they are noncovalently bound dimmers of one 32-34 kDa heavy chain and one 27-30 kDa light chain. MHC Class II is primarily expressed on B cells and antigen presenting cells (APCs).1; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
• Purification method
  N/A
• Form Appearance
  Fluorescein (FITC) Conjugate
• Concentration
  N/A
• Storage and shipping
  The purified (UNLB) antibody is supplied as 0.5 mg of purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C. The fluorescein (FITC) conjugate is supplied as 0.5 mg in 1.0 mL of PBS/NaN3. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. The R-phycoerythrin (R-PE) conjugate is supplied as 0.1 mg in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store the antibody ats should be kept in the range of 1-7 degrees Celsius.. Do not freeze! Protect conjugated forms from light. Each reagent is stable for the period shown on the bottle label if stored as directed.
• Tested applications
  Flow Cytometry; Immunoblot; Immunohistochemistry; Immunoprecipitation
• Description
  This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided. Antibody for research use.
• Properties
  Chickens like all bird species have IgY antibodies that are very stable and found in the yolk. Gallus Gallus domestica is the Latin name of the Chicken. This MBS Monoclonals Fluorescein isothiocyanate (FITC) antibody is currently after some BD antibodies the most commonly used fluorescent dye for FACS. When excited at 488 nanometers, FITC has a green emission that's usually collected at 530 nanometers, the FL1 detector of a FACSCalibur or FACScan. FITC has a high quantum yield (efficiency of energy transfer from absorption to emission fluorescence) and approximately half of the absorbed photons are emitted as fluorescent light. For fluorescent microscopy applications, the 1 FITC is seldom used as it photo bleaches rather quickly though in flow cytometry applications, its photo bleaching effects are not observed due to a very brief interaction at the laser intercept. MBS Monoclonals FITC is highly sensitive to pH extremes.
• Conjugation
  Anti-FITC Antibody
• Test
  Mouse or mice from the Mus musculus species are used for production of mouse monoclonal antibodies or mabs and as research model for humans in your lab. Mouse are mature after 40 days for females and 55 days for males. The female mice are pregnant only 20 days and can give birth to 10 litters of 6-8 mice a year. Transgenic, knock-out, congenic and inbread strains are known for C57BL/6, A/J, BALB/c, SCID while the CD-1 is outbred as strain.
• Latin name
  Mus musculus

#

• Gene target
  MHC   Class  
• Gene symbol
  CD74, BTNL2, RFX1
• Short name
  Mouse Anti- MHC Class II-FITC
• Technique
  anti-, Mouse, anti, FITC, antibody to, antibodies, Fluorescein, mouses
• Host
  mouse
• Label
  FITC
• Species
  chicken, Chickens, Mouses
• Alternative name
  Anti-Mouse Anti-Chicken MHC Class II-FITC
• Alternative technique
  murine, antibodies, fluorescine

Gene info

• Identity
  HGNC:1697
• Gene
  CD74
• Long gene name
  CD74 molecule
• Synonyms gene
  • DHLAG
• Synonyms gene name
  • CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)
  • CD74 molecule, major histocompatibility complex, class II invariant chain
• Synonyms
  • CLIP
• Synonyms name
  • HLA-DR-gamma
  • Ia-associated invariant chain
  • gamma chain of class II antigens
  • MHC HLA-DR gamma chain
  • class II MHC-associated invariant chain peptide
• Locus
  5q33.1
• Discovery year
  1986-01-01
• Entrez gene record
  972
• Pubmed identfication
  • 6324166
  • 3001652
• RefSeq identity
  • NM_004355
• Classification
  • CD molecules
• VEGA ID
  OTTHUMG00000163559

Gene info

• Identity
  HGNC:1142
• Gene
  BTNL2
• Long gene name
  butyrophilin like 2
• Synonyms gene name
  • butyrophilin-like 2 (MHC class II associated)
  • butyrophilin-like 2
• Synonyms
  • HSBLMHC1
  • BTL-II
  • BTN7
• GenBank acession
  • AF186588
• Locus
  6p21.32
• Discovery year
  2000-08-22
• Entrez gene record
  56244
• Pubmed identfication
  • 10803852
  • 15735647
• RefSeq identity
  • NM_019602
• Classification
  • Butyrophilins
  • C2-set domain containing
  • V-set domain containing
• VEGA ID
  OTTHUMG00000031102

Gene info

• Identity
  HGNC:9982
• Gene
  RFX1
• Long gene name
  regulatory factor X1
• Synonyms gene name
  • regulatory factor X, 1 (influences HLA class II expression)
• Synonyms
  • EF-C
• Synonyms name
  • trans-acting regulatory factor 1
  • enhancer factor C
  • MHC class II regulatory factor RFX
• Locus
  19p13.12
• Discovery year
  1991-11-06
• Entrez gene record
  5989
• Pubmed identfication
  • 1505960
  • 8289803
• RefSeq identity
  • NM_002918
• Classification
  • Regulatory factor X family
• VEGA ID
  OTTHUMG00000181979

MeSH Data

• Name
  Cytophotometry
• Concept
  Scope note: A method for the study of certain organic compounds within cells, in situ, by measuring the light intensities of the selectively stained areas of cytoplasm. The compounds studied and their locations in the cells are made to fluoresce and are observed under a microscope.
• Tree numbers
  • E01.370.225.500.386
  • E05.196.712.516.600.240
  • E05.200.500.386
  • E05.242.386
• Qualifiers
  ethics, trends, veterinary, history, classification, economics, instrumentation, methods, standards, statistics & numerical data

Product images

Similar products