hCD70-muCD8 Fusion Protein (human CD70-murine CD8 Fusion Protein)

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Description

Cytotoxic T cells cluster differentiators for flow cytometry. This transmembrane glycoprotein is detected by monoclonals and has a lot of clones available with different affinity. Fusion proteins or chimeric proteins are proteins created through the joining of two or more genes that originally coded for separate proteins. A GFP gene is often used as tag to a reporter gene. Fusion lentiverctors can be used as viral particles to produce proteins that carry for example a GFP tag. Antigen purification of recombinant fusion tag proteins is a frequent strategy using a Fralg tag.
Properties

Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Gene target

hCD70-muCD8 Protein CD70-murine CD8 Protein
Gene symbol

CD70, CD8A
Short name

hCD70-muCD8 Protein ( CD70-murine CD8 Protein)
Species

Human, Humans
Alternative name

hCD70-muCD8 Fusion Protein (H. sapiens CD70 molecule-murine CD8 Fusion Protein)
Alternative to gene target

CD70 molecule, CD27L and CD27LG and TNFSF7, CD70 and IDBG-21699 and ENSG00000125726 and 970, protein binding, Extracellular, Cd70 and IDBG-193725 and ENSMUSG00000019489 and 21948, CD70 and IDBG-643945 and ENSBTAG00000009752 and 522074

Identity

HGNC:1706
Gene

CD8A
Long gene name

CD8a molecule
Synonyms gene
- CD8
Synonyms gene name
- CD8 antigen, alpha polypeptide (p32)
- T-cell surface glycoprotein CD8 alpha chain
Locus

2p11.2
Discovery year

1986-01-01
Entrez gene record

925
Pubmed identfication
- 1541829
RefSeq identity
- NM_001768
Classification
- V-set domain containing
- CD molecules
VEGA ID

OTTHUMG00000130265
Locus Specific Databases
- CD8Abase: Mutation registry for CD8 deficiency
- LRG_44