GYY 4137 for cell activation

GYY 4137 for cell activation is available 2 times from Biovision labs

1908-25 | GYY 4137 for cell activationsize: 25 mg | 384.52 USD

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1908-5 | GYY 4137 for cell activationsize: 5 mg | 142.28 USD

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  • Description
    A slow-releasing, water-soluble hydrogen sulfide (H₂S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various proinflammatory mediators (such as IL-1β, IL-6, TNF-α, nitric oxide (NO) and PGE2) in RAW264.7 cells. Increases the synthesis of the anti-inflammatory chemokine IL-10 through NF-κB, ATF-2 and HSP27 dependent pathways in RAW264.7 cells.
  • Peptide sequence
    N/A
  • CAS number
    106740-09-4
  • Molecular weight
    376.47
  • Category
    Biochemicals
  • Other name
    p-​Methoxyphenyl)morpholino-​phosphinodithioic acid
  • Molecular formula
    C₁₁H₁₅NO₂PS₂ · C₄H₁₀NO
  • Physical appearance
    White solid
  • Supplied with
    N/A
  • Is this a salt?
    No
  • Is it cell-permeable?
    Yes
  • Purification
    ≥95% by HPLC
  • Reconstitute instructions
    DMSO (15 mg/ml) or water (30 mg/ml)
  • Storage condition
    -20°C
  • Shipping condition
    gel pack
  • Maximum time for storage
    36 months
  • Storage instructions
    Protect from air and moisture
  • Additional description
    For cells, cell lines and tissues in culture till half confluency.
  • Gene target
  • Short name
    GYY 4137 for activation
  • Technique
    activation
  • Alternative name
    GYY 4137 to measure cellular activation
  • Tissue
    cell
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