GBA/Acid beta-glucosidase

• Catalog number
  bs-11779R
• Price
  Please ask
• Size
  0.1ml

• Long name
  GBA/Acid beta-glucosidase
• Also known as
  GBA/Acid beta-glucosidase
• Category
  Primary Antibodies
• Conjugation
  Unconjugated
• Target Antigen
  GBA/Acid beta-glucosidase
• Specificity
  This is a highly specific antibody against GBA/Acid beta-glucosidase.
• Modification s
  None
• Modification site s
  Unmodified antibody
• Clonality
  Polyclonal antibody
• Clone number
  Polyclonal antibody
• Concentration
  1ug per 1ul
• Source
  This antibody was obtained by immunization of the host with KLH conjugated synthetic peptide derived from human Acid beta-glucosidase
• Tested Applications
  WB, IHC-P, IF(IHC-P)
• Recommended dilutions
  WB(1:100-1000), IHC-P(1:100-500), IF(IHC-P)(1:50-200)
• Cross reactivity
  Human, Mouse, Rat
• Cross reactive species details
  Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
• Background of the target antigen
  Beta-Glucosidase is a predominantly liver enzyme which efficiently hydrolyzes Beta-D-glucoside and Beta-D-galactoside. Defects in Beta-Glucosidase cause Gaucher disease, an inherited condition distinguished by the accumulation of glucosylceramide within the cells of the reticuloendothelial system. Beta-Glucosidase is used in enzyme replacement treatment aimed at treating Gaucher disease. The absorption of dietary flavonoid glycosides in humans involves a critical deglycosylation step that is mediated by epithelial Beta-glucosidases.
• Purification method
  This antibody was purified via Protein A.
• Storage conditions
  Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
• Synonym names
  Acid beta glucosidase; Acid beta-glucosidase; Alglucerase; Beta glucocerebrosidase; BETA GLUCOSIDASE, ACID; Beta-glucocerebrosidase; betaGC; D glucosyl N acylsphingosine glucohydrolase; D-glucosyl-N-acylsphingosine glucohydrolase; EC 3.2.1.45 ; GBA; Gba protein; GBA1; GC antibody GCase; GCB; GLCM_HUMAN; GLUC; Glucocerebrosidase alt.; Glucocerebrosidase; GLUCOCEREBROSIDASE PSEUDOGENE; Glucosidase beta; Glucosidase, beta, acid; Glucosidase, beta; acid includes glucosylceramidase; Glucosylceramidase; Imiglucerase; Lysosomal glucocerebrosidase.

• Gene target
  GBA/Acid   beta-glucosidase  
• Gene symbol
  GBA
• Short name
  Anti-GBA/Acid beta-glucosidase
• Host
  Rabbit (Oryctolagus cuniculus)
• Isotype
  Immunoglobulin G (IgG)
• Alternative name
  GBA/Acid beta-glucosidase

Gene info

• Identity
  HGNC:4177
• Gene
  GBA
• Long gene name
  glucosylceramidase beta
• Synonyms gene
  • GLUC
• Synonyms gene name
  • glucosylceramidase
  • glucosidase, beta; acid (includes glucosylceramidase)
  • glucosidase, beta, acid
• Synonyms
  • GBA1
• Synonyms name
  • glucocerebrosidase
• GenBank acession
  • M19285
• Locus
  1q22
• Discovery year
  1986-01-01
• Entrez gene record
  2629
• Pubmed identfication
  • 3359914
• RefSeq identity
  • NM_000157
• Classification
  • Glycoside hydrolases
• VEGA ID
  OTTHUMG00000035841

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