GAPDH Polyconal Antibody

GAPDH Polyconal Antibody is available 1 time from Bioss primary unconjugated antibodies labs

bs-10900R | GAPDH Polyconal Antibodysize: 0.1ml | 309.63 USD

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  • Long name
    GAPDH Polyconal Antibody
  • Also known as
    GAPDH Polyconal Antibody
  • Category
    Primary Antibodies
  • Conjugation
    Unconjugated
  • Target Antigen
    GAPDH
  • Specificity
    This is a highly specific antibody against GAPDH.
  • Modification(s)
    None
  • Modification site(s)
    Unmodified antibody
  • Clonality
    Polyclonal antibody
  • Clone number
    Polyclonal antibody
  • Concentration
    1ug per 1ul
  • Source
    Recombinant full length human GAPDH
  • Gene ID number
    2597
  • Swiss Prot
    P04406
  • Tested Applications
    WB
  • Recommended dilutions
    WB(1:100-1000)
  • Cross reactivity
    Human, Mouse, Rat
  • Cross reactive species details
    Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
  • Background of the target antigen
    Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC. Modulates the organization and assembly of the cytoskeleton. Facilitates the CHP1-dependent microtubule and membrane associations through its ability to stimulate the binding of CHP1 to microtubules (By similarity). Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate. Component of the GAIT (gamma interferon-activated inhibitor of translation) complex which mediates interferon-gamma-induced transcript-selective translation inhibition in inflammation processes. Upon interferon-gamma treatment assembles into the GAIT complex which binds to stem loop-containing GAIT elements in the 3'-UTR of diverse inflammatory mRNAs (such as ceruplasmin) and suppresses their translation.
  • Purification method
    This antibody was purified via Protein A.
  • Storage conditions
    Keep the antibody in aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for up to 1 year.
  • Synonym names
    Glyceraldehyde-3-phosphate dehydrogenase; GAPDH; Peptidyl-cysteine S-nitrosylase GAPDH; GAPD; CDABP0047; OK/SW-cl.12
  • Properties
    If you buy Antibodies supplied by Bioss Primary Unconjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
  • French translation
    anticorps
  • Gene target
  • Short name
    GAPDH Polyconal Antibody
  • Technique
    Antibody
  • Alternative name
    GAPDH Polyconal (Antibody to)
  • Alternative technique
    antibodies
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